Combined AIIMS - 2020 (Jodhpur, Bhopal, Patna, Raipur)
Applied Nutrition & Dietetics
Easy

Which of the following vitamin deficiency causes Bitot's spot and Xerophthalmia?

Appeared in: Combined AIIMS - 2020 (Jodhpur, Bhopal, Patna, Raipur)

Explanation

  • Vitamin A deficiency causes a spectrum of eye disorders known as Xerophthalmia, which means 'dry eye'.
  • Bitot's spots are a specific and characteristic sign of Vitamin A deficiency. They appear as triangular, foamy, white patches on the conjunctiva.
  • Vitamin A is crucial for vision, particularly in dim light, as it is a component of the retinal pigment rhodopsin. It also maintains the health of epithelial tissues like the conjunctiva and cornea.
  • The progression of eye damage from Vitamin A deficiency is predictable, starting with night blindness and advancing to irreversible blindness if not treated.

Why Other Options Were Wrong

  • Option A: Vitamin D deficiency primarily affects bone health, not the eyes in the manner described.
  • Option B: Vitamin K is essential for blood clotting. Its deficiency leads to bleeding disorders, not Bitot's spots.
  • Option D: Vitamin E deficiency is rare and is primarily associated with neurological problems and hemolytic anemia, not specific ocular signs like Bitot's spots.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Ocular manifestations of Vitamin A deficiency as background academic context rather than a clinical decision trigger.
  • Nurses play a vital role in nutritional screening and identifying patients at risk for vitamin deficiencies, especially children and pregnant women in underserved communities.
  • Patient education is a key nursing responsibility. This includes teaching families about affordable, locally available dietary sources of Vitamin A, such as dark green leafy vegetables, carrots, sweet potatoes, mangoes, and papaya.
  • Early recognition of signs like night blindness can prevent progression to irreversible blindness. A nurse is often the first healthcare professional to hear a mother's concern about her child's inability to see in the evening.
How to Approach the Question
  • First, identify the key clinical terms in the question: 'Bitot's spot' and 'Xerophthalmia'.
  • Recognize that these are highly specific, classic signs of a particular nutritional deficiency.
  • Systematically review the functions and deficiency diseases of the fat-soluble vitamins listed in the options (A, D, E, K).
  • Recall that Vitamin A is directly linked to vision and eye health. Match the specific signs (Bitot's spot, Xerophthalmia) to Vitamin A deficiency.
  • Eliminate the other options by confirming their primary roles: Vitamin D for bone health (Rickets), Vitamin K for blood clotting, and Vitamin E as an antioxidant with neurological roles.
  • Confirm your choice. The unique and specific nature of Bitot's spots makes Vitamin A the only plausible answer.
Concept Tested & Keywords
  • Concept Tested: Ocular manifestations of Vitamin A deficiency
  • Stem keywords: vitamin deficiency, Bitot's spot, Xerophthalmia
  • Lead-in keywords: Which of the following
  • Negative lead-in flag: false

Question ID

QlcuMBZWvcx7T_l32lzlw-

Reference Book

E6 Parks TextBook of Preventive & Social Medicine part 2 — Subpart A (pp 1-232 of 464) p. 151-153

E6 Textbook of Biochemistry for medical StudentsDM Vasudevan Part 2 — Subpart A (pp 1-239 of 478) p. 121-123

Practise the full Combined AIIMS - 2020 (Jodhpur, Bhopal, Patna, Raipur)

Attempt every question from this paper in a timed mock, then review the full solution for each one.