RRB Staff Nurse Jaipur-6th June 2018
Pharmacology
Easy

Penicillin was discovered by

Appeared in: RRB Staff Nurse Jaipur-6th June 2018

Explanation

  • Sir Alexander Fleming, a Scottish physician and microbiologist, discovered penicillin in 1929.
  • The discovery was accidental; he observed that the mold Penicillium notatum inhibited the growth of Staphylococcus bacteria on a culture plate.
  • This substance, penicillin, was the world's first mass-produced antibiotic.
  • For their work on penicillin, Fleming, Howard Florey, and Ernst Chain were awarded the Nobel Prize in Physiology or Medicine in 1945.

Why Other Options Were Wrong

  • Option A: Michael Faraday was a physicist and chemist, not a microbiologist. His work was foundational to the fields of electromagnetism and electrochemistry.
  • Option C: William Harvey was an English physician who made seminal contributions to anatomy and physiology.
  • Option D: Charles Goodyear was an American self-taught chemist and manufacturing engineer who developed vulcanized rubber.

Related Visual

Visual explanation — Related Visual
  • Visual 1: Photograph - A portrait of Sir Alexander Fleming, which helps students associate the name with the person.
  • Visual 2: Diagram - An illustration of Fleming's original petri dish showing the zone of inhibition where the Penicillium mold stopped bacterial growth, visually explaining the discovery.
Clinical Relevance
  • Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain History of Microbiology and Pharmacology as background academic context rather than a clinical decision trigger.
  • The discovery of penicillin marked the beginning of the antibiotic era, which revolutionized medicine by providing effective treatment for previously fatal bacterial infections.
  • As a nurse, it is critical to assess for penicillin allergies before administration, as it is one of the most common drug allergies and can cause life-threatening anaphylaxis.
  • Understanding the history of antibiotics helps in appreciating the current challenge of antimicrobial resistance, a major global health threat.
How to Approach the Question
  • This is a factual recall question based on the history of medicine.
  • Identify the key term in the question stem: 'Penicillin'.
  • Scan the options, which are all names of famous historical figures.
  • Access your knowledge base to link the discovery of penicillin to the correct scientist.
  • Sir Alexander Fleming is universally credited with the discovery of penicillin.
  • Eliminate the other options by recalling their distinct and unrelated contributions: Faraday (physics), Harvey (blood circulation), and Goodyear (vulcanized rubber).
Concept Tested & Keywords
  • Concept Tested: History of Microbiology and Pharmacology
  • Stem keywords: Penicillin, discovered
  • Lead-in keywords: BEST, MOST RELEVANT CLUE
  • Negative lead-in flag: false

Question ID

QEv6yegHZNu6GnOUXdXVUC

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Attempt every question from this paper in a timed mock, then review the full solution for each one.