UP CHO - 2018
Pharmacology
Easy

A CHO/nurse is caring for a patient with swine flu and knows that the most useful/effective drug for swine flu is?

Appeared in: UP CHO - 2018

Explanation

  • Oseltamivir is a neuraminidase inhibitor, a class of antiviral drugs that specifically targets influenza viruses.
  • It is effective against both Influenza A and B, which includes the H1N1 strain, commonly known as swine flu.
  • The drug works by preventing the release of new virus particles from infected cells, thereby limiting the spread of the infection within the body.
  • For maximum effectiveness in treating influenza, Oseltamivir should be initiated within 48 hours of the first appearance of symptoms.
  • It is considered the first-line antiviral of choice for the treatment and prophylaxis of influenza, including pandemic strains like H1N1.

Why Other Options Were Wrong

  • Option A: Acyclovir is an antiviral medication, but its spectrum of activity is limited to the herpesvirus family.
  • Option B: Adefovir is specifically designed to combat the Hepatitis B virus (HBV) and has no efficacy against influenza viruses.
  • Option C: Cidofovir is a potent antiviral used for severe DNA virus infections, but it is not indicated for influenza and carries a high risk of nephrotoxicity.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: Use the key finding related to Pharmacological management of Swine Flu (H1N1 Influenza) to guide bedside assessment, documentation, and the next nursing action.
  • Prompt identification and treatment of influenza are critical, especially in high-risk populations, to prevent severe complications like pneumonia, respiratory failure, and death. Oseltamivir is a key tool in this effort.
  • Nurses play a vital role in implementing infection control measures, such as droplet precautions and patient education on hygiene, to prevent the nosocomial spread of influenza.
  • What if? If the patient was pregnant, Oseltamivir is still the recommended antiviral for influenza treatment, as the benefits of treating influenza in pregnancy are considered to outweigh the potential risks of the medication.
How to Approach the Question
  • First, identify the core of the question: it asks for the specific drug used to treat 'swine flu'.
  • Recognize that 'swine flu' is the common name for the H1N1 strain of the Influenza A virus.
  • Next, evaluate the options provided. All are antiviral drugs, so you need to differentiate them based on their specific targets.
  • Recall or deduce the primary use for each drug. Oseltamivir is famously associated with 'flu'. Acyclovir is for herpes, Adefovir for Hepatitis B, and Cidofovir for CMV.
  • Based on this differentiation, conclude that Oseltamivir is the only drug listed that is effective against the influenza virus.
  • Confirm your choice by remembering that neuraminidase inhibitors (like Oseltamivir) are the standard treatment for influenza.
Concept Tested & Keywords
  • Concept Tested: Pharmacological management of Swine Flu (H1N1 Influenza).
  • Stem keywords: swine flu, drug, effective
  • Lead-in keywords: most useful/effective
  • Negative lead-in flag: false

Question ID

Q_L56mINB0tXOLgsHRsVDh

Reference Book

E6 Nelson Textbook of Pediatrics(2024) — Volume 1 p. 1961-1963

E6 Medicine Harrison 22e Part 1 pp. 1578-1580, 1529-1531

Practise the full UP CHO - 2018

Attempt every question from this paper in a timed mock, then review the full solution for each one.

A CHO/nurse is caring for a patient with swine flu and knows that the most useful/effective drug for swine fl… - UP CHO - 2018 | NPrep