AIIMS Delhi NO- 2019
Pharmacology
Easy

A nurse is advised to administer inj. Metronidazole to a patient. She knows action of this is:

Appeared in: AIIMS Delhi NO- 2019

Explanation

  • Metronidazole is classified as a nitroimidazole antimicrobial, which functions as both an antibiotic and an antiprotozoal agent.
  • It is highly effective against anaerobic bacteria (e.g., Bacteroides, Clostridioides) and protozoa (e.g., Trichomonas, Giardia).
  • Its mechanism involves disrupting the DNA synthesis of susceptible microorganisms, which ultimately leads to cell death.
  • This makes 'Antibiotic' the correct description of its primary action in a clinical setting for treating bacterial infections.

Why Other Options Were Wrong

  • Option A: An analgesic is a drug that relieves pain. Metronidazole does not have pain-relieving properties.
  • Option B: An antipyretic is a drug that reduces fever. While an infection treated by Metronidazole may cause a fever, the drug itself does not directly act to lower the fever; the fever resolves as the infection is cleared.
  • Option D: A sedative is a drug that induces calmness or sleep. Metronidazole has no sedative effects; in fact, some of its side effects can include dizziness or headache, but not sedation.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: Use the key finding related to Pharmacological classification and action of Metronidazole to guide bedside assessment, documentation, and the next nursing action.
  • A key nursing responsibility when administering Metronidazole is patient education, particularly advising patients to avoid alcohol completely during therapy and for at least 36-48 hours after the last dose to prevent a disulfiram-like reaction (severe nausea, vomiting, flushing, headache).
  • Nurses should monitor for common side effects like metallic taste, nausea, and gastrointestinal upset, as well as more severe but rare effects like peripheral neuropathy or seizures, especially with long-term use.
  • What if? If a patient on Metronidazole reports numbness and tingling in their hands and feet, the nurse must recognize this as a potential sign of peripheral neuropathy, a serious adverse effect. The nurse should withhold the next dose and notify the prescriber immediately for further assessment.
How to Approach the Question
  • First, identify the core of the question, which is to classify the drug Metronidazole based on its action.
  • Recall or look up the pharmacological class of Metronidazole. You might remember it's used for specific types of infections.
  • Evaluate each option: 'Analgesic' means pain relief, 'Antipyretic' means fever reduction, 'Antibiotic' means it fights bacterial infections, and 'Sedative' means it causes sleepiness.
  • Connect the known use of Metronidazole (treating infections) with the provided options.
  • Eliminate the options that do not match its primary function. Metronidazole is not used for pain, fever, or sedation.
  • Conclude that its action against bacteria makes it an antibiotic.
Concept Tested & Keywords
  • Concept Tested: Pharmacological classification and action of Metronidazole.
  • Stem keywords: Metronidazole, action
  • Lead-in keywords: action of this is
  • Negative lead-in flag: false

Question ID

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Reference Book

E6 Pharmacology Nursing Lilley 11e Part 2 p. 322-324

E6 Pharmacology KD Tripathi Essentials 9e Part 3 p. 170-172

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