Paget's Disease is related to which organ?

Appeared in: UP CHO - 2018

Explanation

Paget's disease, also known as osteitis deformans, is a chronic metabolic disorder of the skeleton (bone).
The disease process involves excessive bone breakdown (resorption) by osteoclasts, followed by disorganized and accelerated bone regrowth by osteoblasts.
This abnormal remodeling results in bones that are enlarged, structurally unsound, weak, and prone to deformity and fractures.
Commonly affected areas include the pelvis, spine, skull, and long bones of the legs.

Option B: The brain is not the primary organ affected. Paget's disease is a bone disorder.
Option C: The heart is not the primary organ affected. Paget's disease is a bone disorder.
Option D: The lungs are not involved in the pathophysiology of Paget's disease.

Clinical Relevance

Nursing practice connection: Knowing Organ system affected by Paget's Disease helps nurses interpret findings accurately and avoid errors in routine assessment, medication administration, and patient teaching.
Patient safety is a major nursing concern due to the high risk of pathologic fractures from weakened bones. Implementing fall precautions is essential.
Pain management is a key priority. Nurses administer analgesics and bisphosphonates as prescribed and assess pain levels regularly.
Nurses must monitor for complications. This includes assessing for hearing loss (if the skull is involved), changes in gait, and signs of nerve compression.

How to Approach the Question

This is a factual recall question that tests your knowledge of a specific disease.
First, identify the key term in the question stem: "Paget's Disease".
Recall the definition and primary body system affected by this disease. The alternative name, osteitis deformans, provides a clue, as "osteo-" refers to bone.
Systematically evaluate each option against your knowledge. Paget's disease is a well-known bone disorder.
Eliminate the options that are incorrect. While the heart and brain can be secondarily affected by complications, the primary disease process is in the bone.

Concept Tested & Keywords

QBxmB_mU5ZVGnsBFxEw1EE

E6 Pathology- ROBBINS & COTRAN PATHOLOGIC BASIS OF DISEASE 10TH Ed pp. 1181-1183, 1182-1184

E6 Medicine Harrison 22e Part 2 p. 1217-1219

Practise the full UP CHO - 2018

Attempt every question from this paper in a timed mock, then review the full solution for each one.