NORCET 2 -2021 (Shift-2)
Pharmacology
Easy

Most common side effect of aspirin overdose.

Appeared in: NORCET 2 -2021 (Shift-2)

Explanation

  • Tinnitus, a ringing sensation in the ears, is a hallmark and often the earliest symptom of aspirin (salicylate) toxicity.
  • This symptom is a key feature of 'salicylism', which can develop from either high-dose short-term use or prolonged therapy.
  • It serves as a critical warning sign for both patients and clinicians to suspect overdose and intervene promptly before more severe complications arise.
  • Other early central nervous system effects include dizziness, vertigo, and reversible impairment of hearing and vision.

Why Other Options Were Wrong

  • Option A: While vertigo (dizziness) can occur with aspirin toxicity, it is less specific and not considered the most common or earliest sign compared to tinnitus.
  • Option C: Lacrimation (excessive tearing) is not a recognized or characteristic symptom of aspirin overdose.
  • Option D: Although a headache can be a symptom of salicylate toxicity, it is a very non-specific symptom and is not the most common or characteristic early sign.

Related Visual

Visual explanation — Related Visual
  • Visual 1: Chart - A chart illustrating the progression of aspirin toxicity symptoms from early (tinnitus, hyperventilation) to severe (metabolic acidosis, seizures, coma) correlated with rising serum salicylate levels.
Clinical Relevance
  • Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Signs and symptoms of aspirin (salicylate) overdose as background academic context rather than a clinical decision trigger.
  • Nurses must educate patients on long-term or high-dose aspirin therapy to recognize tinnitus as a key sign of toxicity and to report it immediately.
  • Prompt recognition of salicylate poisoning is crucial because it can progress rapidly to life-threatening metabolic acidosis, respiratory failure, and seizures.
  • What if? - If a patient with arthritis on high-dose aspirin reports hearing loss instead of ringing, the nurse should still suspect salicylate toxicity, as ototoxicity can manifest as both tinnitus and hearing impairment.
How to Approach the Question
  • Identify the core of the question: It asks for the 'most common' side effect of 'aspirin overdose'. This requires identifying the most frequent and characteristic symptom.
  • Recall the classic signs of salicylate (aspirin) toxicity. This is a factual recall question based on pharmacology.
  • Evaluate the options based on their association with aspirin overdose. Consider which symptom is most specifically linked to salicylism.
  • Differentiate between common/early signs and non-specific/late signs. Tinnitus is widely known as the hallmark early symptom.
  • Vertigo and headache are possible but less specific. Lacrimation is not associated.
  • Select the option that represents the most classic and frequently cited symptom in medical and nursing literature.
Concept Tested & Keywords
  • Concept Tested: Signs and symptoms of aspirin (salicylate) overdose.
  • Stem keywords: aspirin overdose, side effect, common
  • Lead-in keywords: Most common

Question ID

QRMm7SGShHaTo8BncFv1n5

Practise the full NORCET 2 -2021 (Shift-2)

Attempt every question from this paper in a timed mock, then review the full solution for each one.

More Autacoids & Related Drugs Questions

More NORCET 2 -2021 (Shift-2) Questions