NCL (MP) Nursing Officer - 2019
Pharmacology
Easy

A nurse is caring for a patient with 'swine flu' and she has to give the drug of choice for swine flu and it is?

Appeared in: NCL (MP) Nursing Officer - 2019

Explanation

  • Swine flu is a type of influenza caused by the H1N1 virus strain.
  • Oseltamivir is the recommended first-line antiviral drug for treating influenza A and B, which includes the H1N1 (swine flu) strain.
  • It functions as a neuraminidase inhibitor, preventing the release of new virus particles from infected cells and thereby halting the spread of the infection.
  • Treatment with Oseltamivir is most effective when initiated within the first 48 hours of symptom onset.

Why Other Options Were Wrong

  • Option A: Acyclovir is an antiviral medication, but its spectrum of activity is against herpesviruses.
  • Option B: Adefovir is an antiviral agent specifically used to treat a liver infection, not a respiratory virus like influenza.
  • Option C: Cidofovir is a potent, broad-spectrum antiviral used for severe viral infections in immunocompromised individuals, but it is not a primary treatment for influenza due to its toxicity profile.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: Use the key finding related to Pharmacological treatment for Influenza A (H1N1), also known as swine flu to guide bedside assessment, documentation, and the next nursing action.
  • Nurses must administer Oseltamivir promptly, ideally within 48 hours of symptom onset, to maximize efficacy and reduce the severity and duration of illness.
  • A key nursing responsibility is implementing strict droplet precautions (e.g., surgical mask, single room) to prevent nosocomial spread of the highly contagious influenza virus.
  • Patient education is crucial; the nurse must instruct the patient to complete the full course of Oseltamivir to prevent the development of antiviral resistance.
How to Approach the Question
  • First, identify the specific disease mentioned in the question, which is 'swine flu'.
  • Recall that swine flu is a strain of the Influenza A virus (H1N1).
  • The question asks for the 'drug of choice', indicating a need to identify the first-line pharmacological treatment.
  • Evaluate the given options, which are all antiviral drugs.
  • Differentiate the drugs based on their specific indications. Recall or deduce that Oseltamivir is for influenza, Acyclovir is for herpes, Adefovir is for Hepatitis B, and Cidofovir is for CMV.
  • Select Oseltamivir as it is the only option indicated for the treatment of Influenza A.
Concept Tested & Keywords
  • Concept Tested: Pharmacological treatment for Influenza A (H1N1), also known as swine flu.
  • Stem keywords: swine flu, drug of choice
  • Lead-in keywords: is

Question ID

QrRZruY1Rn18pJUV9ICnWw

Reference Book

E6 Nelson Textbook of Pediatrics(2024) — Volume 1 p. 1961-1963

E6 Medicine Harrison 22e Part 1 p. 1578-1580

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