Transportation of triglycerides from liver to adipose tissues is the function of which of the following lipoproteins?

Appeared in: AIIMS Bhopal NO - 2018 (Shift-1st)

Explanation

Very Low-Density Lipoprotein (VLDL) is synthesized and secreted by the liver.
Its primary function is to transport endogenous triglycerides (fats made by the body) from the liver to peripheral tissues.
In peripheral tissues like adipose tissue and muscle, an enzyme called lipoprotein lipase breaks down the triglycerides in VLDL, releasing fatty acids for storage or energy use.

Option B: High-Density Lipoprotein (HDL) is primarily involved in reverse cholesterol transport, meaning it carries cholesterol from the body's tissues back to the liver for disposal, not triglycerides from the liver to the tissues.
Option C: Low-Density Lipoprotein (LDL) is the main transporter of cholesterol (not triglycerides) to the peripheral tissues. High levels are associated with atherosclerosis.
Option D: Intermediate-Density Lipoprotein (IDL) is a short-lived remnant particle formed when VLDL gives up its triglycerides. It is not the primary lipoprotein for transporting triglycerides from the liver.

Clinical Relevance

Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Lipoprotein Metabolism and Transport as background academic context rather than a clinical decision trigger.
Understanding lipoprotein function is crucial for interpreting a patient's lipid profile, which is a key indicator of cardiovascular disease risk.
Elevated levels of VLDL (and therefore triglycerides) and LDL are linked to an increased risk of atherosclerosis, heart attack, and stroke.
Nursing interventions for patients with high VLDL often involve patient education on diet (reducing saturated fats and simple carbohydrates), exercise, and medication adherence (e.g., statins, fibrates).

How to Approach the Question

This is a factual recall question that tests your knowledge of biochemistry.
First, identify the key components of the question: the substance being transported (triglycerides), the origin (liver), and the destination (adipose tissues).
Next, systematically recall the primary function of each lipoprotein listed in the options.
VLDL: Transports triglycerides from the liver.
HDL: Transports cholesterol back to the liver (reverse transport).
LDL: Transports cholesterol to the tissues.

Concept Tested & Keywords

Concept Tested: Lipoprotein Metabolism and Transport
Stem keywords: Transportation, triglycerides, liver, adipose tissues, lipoproteins
Lead-in keywords: function of

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Practise the full AIIMS Bhopal NO - 2018 (Shift-1st)

Attempt every question from this paper in a timed mock, then review the full solution for each one.