UPPSC 2023
Pharmacology
Easy

All of the following drugs should be given to the patients of bronchial asthma, except -

Appeared in: UPPSC 2023

Explanation

  • Aspirin, a Non-Steroidal Anti-Inflammatory Drug (NSAID), is contraindicated in many patients with asthma.
  • It can trigger a severe reaction known as Aspirin-Exacerbated Respiratory Disease (AERD).
  • This occurs because Aspirin blocks the COX enzyme, leading to an overproduction of leukotrienes, which are powerful substances that cause severe airway narrowing (bronchoconstriction).

Why Other Options Were Wrong

  • Option A: This is an appropriate medication for asthma.
  • Option B: This is an appropriate medication for asthma.
  • Option D: This is an appropriate medication for asthma.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Pharmacotherapy for bronchial asthma, focusing on contraindications as background academic context rather than a clinical decision trigger.
  • A crucial nursing responsibility is to obtain a thorough medication history, specifically asking asthmatic patients about reactions to Aspirin or other NSAIDs (like ibuprofen) before administration.
  • Patient education is vital. Nurses must teach patients with known aspirin sensitivity to read labels of over-the-counter pain and cold medications, as many contain hidden NSAIDs.
  • What if? If a patient with asthma also has arthritis requiring pain management, the nurse should anticipate collaborating with the provider to select a safer analgesic, such as acetaminophen or a selective COX-2 inhibitor (with caution), instead of a traditional NSAID.
How to Approach the Question
  • First, identify the core subject of the question: drugs for bronchial asthma.
  • Recognize the keyword 'except'. This means three of the options are used to treat asthma, and one is not (or is contraindicated).
  • Evaluate each option's role in asthma management.
  • Recall that Fluticasone is an inhaled steroid, a standard controller.
  • Recall that Terbutaline is a beta-agonist, a standard reliever.
  • Recall that Theophylline is a methylxanthine, a classic asthma drug.
Concept Tested & Keywords
  • Concept Tested: Pharmacotherapy for bronchial asthma, focusing on contraindications.
  • Stem keywords: drugs, bronchial asthma
  • Lead-in keywords: except
  • Negative lead-in flag: The question is negatively framed using the word 'except', which means you must find the option that is NOT a treatment for bronchial asthma.

Question ID

Q1PAVfMdsURHj0Z94YDmPk

Reference Book

E6 Ghai Essential Pediatrics(pp 26-904 of 913) p. 409-411

E6 Pharmacology KD Tripathi Essentials 9e Part 1 p. 272-274

Practise the full UPPSC 2023

Attempt every question from this paper in a timed mock, then review the full solution for each one.

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