AIIMS Nagpur NO- 2020
Obstetrics & Gynaecology
Easy

Acidic medium of vagina is maintained by:

Appeared in: AIIMS Nagpur NO- 2020

Explanation

  • Doderlein's bacilli are a specific group of Lactobacillus species that constitute the normal, healthy flora of the vagina.
  • These bacteria metabolize glycogen present in the vaginal epithelial cells into lactic acid.
  • The production of lactic acid is the primary mechanism that maintains the vagina's acidic pH, typically between 3.8 and 4.5.
  • This acidic environment is crucial as it inhibits the growth of pathogenic bacteria and other microorganisms, providing a natural defense against infections.

Why Other Options Were Wrong

  • Option A: Trichomonas vaginalis is a pathogenic protozoan, not a part of the normal flora. It causes the sexually transmitted infection trichomoniasis, which leads to inflammation and an increase in vaginal pH, making the environment more alkaline and susceptible to other infections.
  • Option B: E. coli is a bacterium commonly found in the gastrointestinal tract. Its presence in the vagina is abnormal and can lead to urinary tract infections (UTIs) or aerobic vaginitis. It does not contribute to maintaining acidity; instead, its overgrowth is associated with a disruption of the normal flora and an increased pH.
  • Option C: Staphylococci are bacteria typically found on the skin. While they can be present in the vagina, they are not the primary organisms responsible for maintaining its acidic pH. Certain species, like Staphylococcus aureus, can cause infections (e.g., aerobic vaginitis or toxic shock syndrome) and disrupt the normal vaginal environment.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Normal vaginal flora and pH regulation as background academic context rather than a clinical decision trigger.
  • Understanding the role of Doderlein's bacilli is fundamental for nurses in patient education regarding vaginal health and hygiene.
  • Nurses should advise patients to avoid practices that disrupt the normal vaginal flora, such as douching or using harsh soaps, as this can kill beneficial lactobacilli and increase infection risk.
  • Disruption of the normal acidic pH can lead to conditions like Bacterial Vaginosis (BV), yeast infections (Candidiasis), and increased susceptibility to STIs.
How to Approach the Question
  • First, identify the core concept of the question, which is the mechanism for maintaining the vagina's acidic environment.
  • Recall the composition of the normal vaginal flora and the function of its key components.
  • The term 'acidic medium' should trigger the memory of lactic acid production.
  • Evaluate each option based on its known role in the vaginal ecosystem. Doderlein's bacilli is another name for vaginal lactobacilli.
  • Eliminate the options that are known pathogens (Trichomonas vaginalis) or are associated with abnormal conditions and a higher pH (E. coli, Staphylococci).
  • Select the option that is directly responsible for producing acid and maintaining a healthy vaginal environment.
Concept Tested & Keywords
  • Concept Tested: Normal vaginal flora and pH regulation
  • Stem keywords: Acidic medium, vagina, maintained by
  • Lead-in keywords: BEST, MOST RELEVANT CLUE
  • Negative lead-in flag: false

Question ID

QIIxb1mYFRAKg53hkfiwkq

Reference Book

E6 Medicine Harrison 22e Part 1 p. 1142-1144

E6 Gynecology Williams pp. 68-91, 110-135

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