UPPSC 2023
Obstetrics & Gynaecology
Easy

Which hormone is essential for production of milk in mother's breast?

Appeared in: UPPSC 2023

Explanation

  • Prolactin is the key hormone responsible for lactogenesis, which is the process of milk synthesis and production.
  • It is secreted by the anterior pituitary gland.
  • Prolactin levels rise during pregnancy to prepare the breasts, but its milk-producing effect is inhibited by high levels of progesterone and estrogen from the placenta.
  • After delivery, the sudden drop in progesterone and estrogen allows prolactin to act on the breast's alveolar cells to initiate copious milk production.

Why Other Options Were Wrong

  • Option A: Follicle-Stimulating Hormone (FSH) is primarily involved in regulating the menstrual cycle and fertility by stimulating ovarian follicle growth. It has no direct function in milk production.
  • Option C: Antidiuretic Hormone (ADH) is responsible for regulating water balance and blood pressure by controlling water reabsorption in the kidneys. It is not involved in the process of lactation.
  • Option D: Oxytocin is crucial for breastfeeding but is responsible for milk ejection (the 'let-down' reflex), not milk production. It causes the myoepithelial cells surrounding the alveoli to contract, squeezing the produced milk into the ducts.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Hormonal regulation of lactation as background academic context rather than a clinical decision trigger.
  • Nurses play a vital role in lactation support. Understanding that suckling stimulates both prolactin and oxytocin helps in educating mothers that frequent and effective breastfeeding is key to establishing and maintaining milk supply.
  • Issues like delayed lactogenesis can be linked to hormonal problems or retained placental fragments (which maintain high progesterone levels, inhibiting prolactin).
  • Stress, pain, or anxiety can inhibit the oxytocin reflex, preventing milk let-down even when the breast is full. Nurses can teach relaxation techniques to facilitate this reflex.
How to Approach the Question
  • First, identify the core process in the question: 'production of milk'.
  • Next, analyze the options provided, which are all hormones.
  • Recall the specific functions of each hormone in relation to reproduction and postpartum physiology.
  • Differentiate between milk 'production' (synthesis) and milk 'ejection' (let-down).
  • Associate Prolactin with 'production' and Oxytocin with 'ejection'.
  • Eliminate FSH and ADH as their primary roles (ovarian cycle and water balance, respectively) are not related to milk production.
Concept Tested & Keywords
  • Concept Tested: Hormonal regulation of lactation
  • Stem keywords: hormone, production of milk, mother's breast
  • Lead-in keywords: Which
  • Negative lead-in flag: false

Question ID

Q4y5YZPIPWvYl6YkXKKWrK

Reference Book

E6 Physiology Guyton 4SAE Part 3 p. 69-71

E6 Physiology Essentials Sembulingam 10e Part 2 p. 150-152

E6 Obstetrics Williams p. 48-68

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