What is the synonym of Clotting Factor II?

Appeared in: AIIMS Patna NO - 2020

Explanation

Clotting Factor II is also known as Prothrombin.
Prothrombin is a vitamin K-dependent protein synthesized by the liver.
It is a zymogen (inactive precursor) that, when activated, is converted to thrombin (Factor IIa).
Thrombin is a key enzyme in the coagulation cascade that converts fibrinogen to fibrin, leading to clot formation.

Option A: Christmas factor is the synonym for Clotting Factor IX, not Factor II.
Option B: Fibrinogen is the name for Clotting Factor I, not Factor II.
Option C: Calcium is Clotting Factor IV, not Factor II.

Clinical Relevance

Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Synonyms of Blood Clotting Factors as background academic context rather than a clinical decision trigger.
Nurses must understand clotting factors to interpret lab results like Prothrombin Time (PT) and International Normalized Ratio (INR), which are critical for monitoring patients on warfarin therapy.
A prolonged PT/INR can indicate a Factor II deficiency, liver disease, or an excessive dose of warfarin, increasing the patient's risk of bleeding.
Knowledge of the clotting cascade helps in recognizing signs of bleeding disorders (e.g., hemophilia) and understanding the mechanism of action of various anticoagulants.

How to Approach the Question

This is a factual recall question that tests your knowledge of medical terminology.
First, identify the core of the question: it asks for the synonym of 'Clotting Factor II'.
Mentally review or look up the list of clotting factors and their common names.
Evaluate each option against your knowledge: Christmas factor is IX, Fibrinogen is I, Calcium is IV.
Identify Prothrombin as the correct synonym for Factor II.
Confirm the answer by recalling the role of prothrombin in the clotting cascade.

Concept Tested & Keywords

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E6 Pharmacology Katzung 16e p. 953-955

E6 Physiology Essentials Sembulingam 10e Part 1 p. 137-139

E6 Textbook of Biochemistry for medical StudentsDM Vasudevan Part 2 — Subpart A (pp 1-239 of 478) p. 65-67

Practise the full AIIMS Patna NO - 2020

Attempt every question from this paper in a timed mock, then review the full solution for each one.