AIIMS Raipur NO- 2019 (shift 3rd)
Pharmacology
Easy

The Bacillus Calmette Guerin vaccine is a live attenuated vaccine that protects against which disease?

Appeared in: AIIMS Raipur NO- 2019 (shift 3rd)

Explanation

  • The Bacillus Calmette-Guérin (BCG) vaccine is a live attenuated vaccine specifically designed to protect against Tuberculosis (TB).
  • It is derived from a weakened strain of Mycobacterium bovis.
  • The primary goal of BCG vaccination, especially in high-prevalence countries, is to prevent severe and disseminated forms of TB in children, such as TB meningitis and miliary TB.
  • The vaccine is administered intradermally, and a characteristic scar at the injection site is a sign of a successful vaccination.

Why Other Options Were Wrong

  • Option A: The BCG vaccine does not protect against Typhoid fever. Typhoid is a bacterial infection caused by Salmonella Typhi.
  • Option B: The BCG vaccine does not protect against Measles. Measles is a viral illness.
  • Option D: The BCG vaccine does not protect against Malaria. Malaria is a parasitic disease transmitted by mosquitoes.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: Knowing BCG Vaccine and Target Disease helps nurses interpret findings accurately and avoid errors in routine assessment, medication administration, and patient teaching.
  • In countries with a high prevalence of TB, like India, BCG vaccination at birth is a critical public health strategy to reduce childhood mortality and morbidity from severe TB.
  • Nurses must educate parents about the normal evolution of the BCG vaccination site (papule to ulcer to scar) to prevent anxiety and unnecessary interventions.
  • The presence of a BCG scar is often used as a marker for prior vaccination during health screenings.
How to Approach the Question
  • This is a factual recall question.
  • Identify the core subject: 'Bacillus Calmette Guerin (BCG) vaccine'.
  • Recall or deduce the primary disease this vaccine targets.
  • The name 'Bacillus' hints at a bacterial origin, which helps in thinking about the target disease.
  • Evaluate the options: Typhoid (bacterial), Measles (viral), Tuberculosis (bacterial), Malaria (parasitic).
  • Connect BCG directly to its well-known target, Tuberculosis, and eliminate the other options which are prevented by different vaccines or have different causative agents.
Concept Tested & Keywords
  • Concept Tested: BCG Vaccine and Target Disease
  • Stem keywords: Bacillus Calmette Guerin vaccine, live attenuated vaccine, protects against
  • Lead-in keywords: which disease
  • Negative lead-in flag: false

Question ID

QFlAgrrddNocCVpUnMhSPv

Reference Book

E6 Medicine Harrison 22e Part 1 p. 1442-1444

E6 Parks TextBook of Preventive & Social Medicine part 1 — Subpart B (pp 202-403 of 604) p. 41-43

E6 Ghai Essential Pediatrics(pp 26-904 of 913) p. 192-194

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