JIPMER Pondicherry NO - 2022
Medical & Surgical Nursing
Easy

In which phase of wound healing does granulation tissue appear?

Appeared in: JIPMER Pondicherry NO - 2022

Explanation

  • The proliferative phase is the third stage of wound healing, focused on filling and covering the wound.
  • This phase is characterized by the formation of granulation tissue, which is a combination of new blood vessels (angiogenesis), fibroblasts, and a new extracellular matrix.
  • Granulation tissue provides the foundation for new tissue growth, wound contraction, and epithelialization (resurfacing of the skin).
  • This phase typically begins 3-4 days after injury and can last for several weeks.

Why Other Options Were Wrong

  • Option A: The inflammatory phase is the second stage, focused on cleaning the wound. Macrophages and neutrophils remove debris and bacteria. While essential for healing, new tissue is not built during this phase.
  • Option B: The hemostasis phase is the immediate, first stage of wound healing. Its sole purpose is to stop the bleeding through vasoconstriction and clot formation.
  • Option C: The maturation phase, or remodeling phase, is the final stage. It involves the reorganization of collagen to increase the tensile strength of the scar. This happens after the granulation tissue has already filled the wound.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: Knowing Phases of Wound Healing helps nurses interpret findings accurately and avoid errors in routine assessment, medication administration, and patient teaching.
  • Nurses assess wound beds to determine the stage of healing. The presence of healthy, beefy red granulation tissue is a key indicator that the wound is in the proliferative phase and healing correctly.
  • Wound care interventions are tailored to the phase of healing. During the proliferative phase, care focuses on protecting the fragile granulation tissue and maintaining a moist environment to support epithelialization.
  • What if? If a wound in the proliferative phase shows pale or dusky granulation tissue, it may indicate poor perfusion or infection. The nurse should reassess the patient's circulation, check for signs of infection, and notify the provider, as the treatment plan may need to be adjusted (e.g., with antimicrobial dressings or debridement).
How to Approach the Question
  • First, identify the keywords in the question: 'phase of wound healing' and 'granulation tissue'.
  • Recall the four main phases of wound healing in chronological order: Hemostasis, Inflammation, Proliferation, and Maturation.
  • Associate the key term 'granulation tissue' with its function. 'Granulation' refers to the granular, bumpy appearance of new tissue growth.
  • Consider the meaning of each phase's name. 'Proliferative' means rapid growth or production of new cells/tissue.
  • Match the event (formation of granulation tissue) with the phase name that best describes it (Proliferative).
  • Eliminate the other options by recalling their primary functions: Hemostasis (stop bleeding), Inflammation (clean wound), and Maturation (remodel scar).
Concept Tested & Keywords
  • Concept Tested: Phases of Wound Healing
  • Stem keywords: wound healing, granulation tissue
  • Lead-in keywords: phase
  • Negative lead-in flag: false

Question ID

QIyCwprjZDfCqBcof-QCyp

Reference Book

E6 PATHOLOGY QUICK REVIEWBased on Harsh Mohan Textbook of PATHOLOGY p. 40-42

E6 Pathology-Textbook of PATHOLOGYHarsh Mohan Part 1 (1-214) p. 135-137

E6 Nursing Fundamentals Potter Perry 12e Part 6 p. 74-76

Practise the full JIPMER Pondicherry NO - 2022

Attempt every question from this paper in a timed mock, then review the full solution for each one.

More Integumentary Function Questions

More JIPMER Pondicherry NO - 2022 Questions