RUHS, Jaipur, M.Sc Nursing Entrance Exam-2023
Medical & Surgical Nursing
Easy

The nurse understands that the patient diagnosed with pulmonary embolism will be treated by

Appeared in: RUHS, Jaipur, M.Sc Nursing Entrance Exam-2023

Explanation

  • IV heparin sodium is the standard-of-care initial anticoagulant for treating acute pulmonary embolism (PE).
  • Its primary function is to prevent the extension of the existing clot and inhibit the formation of new thrombi.
  • Heparin has a rapid onset of action, making it the ideal choice for immediate intervention in acute thromboembolic events.
  • It works by potentiating antithrombin III, which in turn inhibits thrombin and factor Xa, key components of the coagulation cascade.

Why Other Options Were Wrong

  • Option A: Streptokinase is a thrombolytic ('clot-busting') agent, not a first-line anticoagulant. Its use is associated with a high risk of hemorrhage.
  • Option B: Similar to streptokinase, tissue plasminogen activator (tPA) is a powerful thrombolytic agent reserved for severe cases due to a significant risk of bleeding.
  • Option D: Sodium warfarin is an oral anticoagulant with a slow onset of action (taking several days to become therapeutic). It is unsuitable for initial, acute treatment of PE.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: Use the key finding related to Pharmacological Management of Pulmonary Embolism to guide bedside assessment, documentation, and the next nursing action.
  • The nurse's primary role in managing a patient on IV heparin for PE is vigilant monitoring for signs of bleeding (e.g., hematuria, melena, epistaxis, bruising) and ensuring therapeutic aPTT levels.
  • Prompt recognition of PE symptoms (sudden dyspnea, chest pain, tachypnea) and immediate initiation of prescribed anticoagulants are critical to preventing mortality and morbidity.
  • Patient education is crucial, focusing on the importance of adherence to long-term anticoagulation (like warfarin), dietary considerations (Vitamin K intake), and recognizing bleeding risks.
How to Approach the Question
  • First, identify the core clinical condition: pulmonary embolism (PE).
  • The question asks for the standard treatment. This implies the usual, first-line therapy for a typical patient.
  • Differentiate the roles of the medications listed. Categorize them into anticoagulants (prevent clot growth) and thrombolytics (dissolve existing clots).
  • Recognize that anticoagulants are the standard initial therapy for most PEs, while thrombolytics are reserved for more severe, life-threatening situations.
  • Compare the anticoagulants: Heparin has a rapid onset for acute situations, whereas warfarin has a slow onset and is used for long-term management.
  • Based on this, conclude that IV heparin is the appropriate initial treatment for an undifferentiated PE.
Concept Tested & Keywords
  • Concept Tested: Pharmacological Management of Pulmonary Embolism
  • Stem keywords: pulmonary embolism, treated by
  • Lead-in keywords: BEST, MOST RELEVANT CLUE
  • Negative lead-in flag: false

Question ID

QKHe1EuswT4rRR4Ie751ZL

Reference Book

E6 Nursing Brunner Adult Health 3SA Vol 1 Part 2 p. 12-14

E6 Nelson Textbook of Pediatrics(2024) — Volume 2 p. 485-487

E6 Pharmacology Katzung 16e p. 976-978

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