NHM UP Staff Nurse - 2017
Applied Microbiology & Infection control
Easy

Hepatitis B can be prevented by?

Appeared in: NHM UP Staff Nurse - 2017

Explanation

  • Hepatitis B Immune Globulin (HBIG) provides passive immunity against the Hepatitis B virus (HBV).
  • It contains a high concentration of antibodies to HBV (anti-HBs) that offer immediate, though temporary, protection.
  • HBIG is primarily used for post-exposure prophylaxis (PEP) in individuals who have been exposed to the virus, such as through a needlestick injury or at birth to a mother with Hepatitis B.
  • Unlike a vaccine, which stimulates the body to create its own antibodies (active immunity), HBIG provides pre-formed antibodies directly (passive immunity).

Why Other Options Were Wrong

  • Option A: The Measles vaccine provides active immunity against the measles virus (rubeola), not the Hepatitis B virus.
  • Option B: The BCG vaccine is used to prevent severe forms of tuberculosis (TB). It has no efficacy against Hepatitis B.
  • Option C: The DPT vaccine is a combination vaccine that protects against Diphtheria, Pertussis (whooping cough), and Tetanus, not Hepatitis B.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Prevention of Hepatitis B as background academic context rather than a clinical decision trigger.
  • A critical nursing intervention is the prevention of perinatal (mother-to-child) transmission of Hepatitis B.
  • Newborns of HBsAg-positive mothers must receive both HBIG and the first dose of the Hepatitis B vaccine within 12 hours of birth. These injections must be given at separate sites.
  • For occupational exposures like a needlestick injury, immediate administration of HBIG (ideally within 24 hours) and initiation of the Hepatitis B vaccine series (if the person is unvaccinated) is the standard protocol.
How to Approach the Question
  • First, identify the core subject of the question, which is the prevention of a specific disease: Hepatitis B.
  • Next, analyze each option provided. The options are all vaccines or immunological products.
  • Recall or determine the specific disease that each option is designed to prevent.
  • Eliminate the options that are for unrelated diseases (Measles, BCG for TB, DPT for Diphtheria/Pertussis/Tetanus).
  • The remaining option is 'HBIG vaccine'. Recognize that HBIG stands for Hepatitis B Immune Globulin and is indeed used for Hepatitis B prevention, specifically for providing immediate passive immunity after exposure.
  • Even if the term 'vaccine' is used loosely with HBIG, it is the only plausible answer related to Hepatitis B among the choices.
Concept Tested & Keywords
  • Concept Tested: Prevention of Hepatitis B
  • Stem keywords: Hepatitis B, prevented
  • Lead-in keywords: BEST, MOST RELEVANT CLUE

Question ID

QeP_l8yhrpQmQJvyV8Sh6v

Reference Book

E6 Parks TextBook of Preventive & Social Medicine part 1 — Subpart B (pp 202-403 of 604) p. 67-69

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