NORCET 1 - 2020
Pathology & Genetics
Easy

Characteristic of malignant breast cancer?

Appeared in: NORCET 1 - 2020

Explanation

  • Malignant breast tumors are characterized by their invasive nature, causing them to become fixed to underlying tissues like the skin or chest wall, making them non-moveable.
  • The growth pattern of cancer is infiltrative, resulting in poorly defined and irregular borders, unlike the smooth, encapsulated borders of benign tumors.
  • These masses are typically hard and painless in the early stages.

Why Other Options Were Wrong

  • Option B: A regular, well-defined mass is a hallmark of benign conditions like fibroadenomas or cysts, not typically cancer.
  • Option C: This option is internally contradictory; a mass cannot be both moveable and fixed simultaneously.
  • Option D: Both 'moveable' and 'regular' are classic descriptors for a benign breast mass, such as a fibroadenoma.

Related Visual

side comparison showing a cross-section of a breast with a benign smooth, round, mobile mass versus a malignant irregular, spiculated, fixed mass.
Clinical Relevance
  • Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Clinical characteristics of malignant breast masses as background academic context rather than a clinical decision trigger.
  • Nurses play a crucial role in educating patients on the 'Triple Assessment' for breast lumps: clinical examination, imaging (mammogram/ultrasound), and biopsy (histopathology).
  • Early detection is key. A fixed, irregular mass is a significant red flag that requires immediate referral for diagnostic workup.
  • What if? If a patient presents with a moveable, regular, and slightly tender mass that changes with her menstrual cycle, the most likely diagnosis would shift from cancer to a benign condition like a fibroadenoma or fibrocystic changes, though imaging is still warranted to confirm.
How to Approach the Question
  • First, identify the core of the question: it asks for the signs of malignant breast cancer.
  • Recall the pathophysiology of cancer: it is invasive and infiltrative. 'Invasive' means it grows into and gets stuck to other tissues, making it 'fixed' or 'non-moveable'.
  • 'Infiltrative' means its edges are not smooth but 'irregular'.
  • Evaluate each option against these two key concepts: mobility and border regularity.
  • Eliminate options describing benign features (moveable, regular) and contradictory options (moveable and fixed).
Concept Tested & Keywords
  • Concept Tested: Clinical characteristics of malignant breast masses
  • Stem keywords: malignant breast cancer, characteristic
  • Lead-in keywords: Characteristic of
  • Negative lead-in flag: false

Question ID

QkOqw4KRS-dWoivDkOHp5q

Reference Book

E6 Pathology- ROBBINS & COTRAN PATHOLOGIC BASIS OF DISEASE 10TH Ed p. 280-282

E6 Nursing Fundamentals Potter Perry 12e Part 3 p. 105-107

Practise the full NORCET 1 - 2020

Attempt every question from this paper in a timed mock, then review the full solution for each one.