NORCET 3 - 2022 (Shift-2)
Applied Microbiology & Infection control
Easy

Which of the following disease is caused by rat flea?

Appeared in: NORCET 3 - 2022 (Shift-2)

Explanation

  • Endemic typhus, also known as murine typhus, is the disease caused by the bacterium Rickettsia typhi.
  • It is transmitted to humans primarily by the Oriental rat flea, Xenopsylla cheopis.
  • Infection occurs when infected flea feces are rubbed into the flea bite site or other small breaks in the skin.
  • The classic reservoir for R. typhi is the rat, making the rat flea the key vector in its transmission cycle.

Why Other Options Were Wrong

  • Option A: Rocky Mountain spotted fever is a tick-borne disease, not flea-borne. It is caused by Rickettsia rickettsii.
  • Option B: Sleeping sickness, or African trypanosomiasis, is a parasitic disease transmitted by the bite of an infected tsetse fly (Glossina species). It is not caused by a bacterium or transmitted by fleas.
  • Option C: Epidemic typhus is transmitted by the human body louse (Pediculus humanus corporis), not the rat flea. Although it is also a rickettsial disease (Rickettsia prowazekii), its vector and epidemiology are distinct.

Related Visual

Visual explanation — Related Visual
  • Visual 1: Diagram - A chart showing common vector-borne diseases, their causative agents, and the specific arthropod vectors (flea, louse, tick, mosquito, tsetse fly) that transmit them.
Clinical Relevance
  • Nursing practice connection: Knowing Vector-borne diseases and their specific arthropod vectors helps nurses interpret findings accurately and avoid errors in routine assessment, medication administration, and patient teaching.
  • Identifying the correct vector is crucial for public health officials to implement effective control measures, such as rodent and flea control for endemic typhus, or delousing for epidemic typhus.
  • A patient's travel and exposure history (e.g., contact with rats, recent camping, travel to Africa) is a key part of the diagnostic process for febrile illnesses with a rash.
  • What if? If the patient presented with a similar rash and fever but had recently been in an overcrowded, unhygienic refugee camp, the primary suspicion would shift to epidemic (louse-borne) typhus, not endemic (flea-borne) typhus.
How to Approach the Question
  • First, identify the key terms in the question: 'disease' and 'rat flea'.
  • This is a factual recall question that tests your knowledge of microbiology and infectious diseases, specifically vector-borne illnesses.
  • Systematically review the options. For each disease, recall its specific mode of transmission.
  • Recall or deduce that 'Endemic typhus' is classically associated with rats and their fleas.
  • Differentiate it from 'Epidemic typhus', which is associated with human body lice, often in settings of poor hygiene and crowding. The names themselves can be a clue: 'endemic' suggests a stable presence in an animal reservoir, while 'epidemic' suggests rapid human-to-human spread.
  • Eliminate the other options by recalling their vectors: ticks for Rocky Mountain spotted fever and tsetse flies for sleeping sickness.
Concept Tested & Keywords
  • Concept Tested: Vector-borne diseases and their specific arthropod vectors.
  • Stem keywords: disease, rat flea
  • Lead-in keywords: Which
  • Negative lead-in flag: false

Question ID

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Practise the full NORCET 3 - 2022 (Shift-2)

Attempt every question from this paper in a timed mock, then review the full solution for each one.

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Which of the following disease is caused by rat flea? - NORCET 3 - 2022 (Shift-2) | NPrep