DSSSB -28 August 2019 (Shift-2)
Pharmacology
Easy

Ringer's lactate solution contains all of the following constituents, EXCEPT?

Appeared in: DSSSB -28 August 2019 (Shift-2)

Explanation

  • Ringer's Lactate (RL), also known as Hartmann's solution, is a balanced, isotonic crystalloid solution.
  • The standard formulation of Ringer's Lactate does not contain glucose.
  • Its primary constituents are water and electrolytes, including sodium, potassium, chloride, calcium, and lactate.
  • Intravenous solutions that contain glucose along with Ringer's Lactate are distinct formulations, such as Dextrose 5% in Lactated Ringer's (D5LR).

Why Other Options Were Wrong

  • Option A: Chloride (Cl⁻) is a major anion present in Ringer's Lactate solution, typically at a concentration of about 109-111 mEq/L.
  • Option B: Sodium (Na⁺) is the primary cation in Ringer's Lactate, with a concentration of approximately 130-131 mEq/L, which makes the solution isotonic.
  • Option C: Potassium (K⁺) is an important electrolyte included in Ringer's Lactate at a concentration (4-5 mEq/L) that is similar to the normal physiological level in plasma.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Composition of Intravenous Fluids as background academic context rather than a clinical decision trigger.
  • Ringer's Lactate is a first-line fluid for resuscitation in patients with hypovolemia due to dehydration, surgery, burns, or gastrointestinal fluid loss.
  • The lactate in the solution is metabolized by the liver into bicarbonate, which helps to buffer metabolic acidosis. This makes it a more 'balanced' solution compared to Normal Saline, which can cause hyperchloremic metabolic acidosis in large volumes.
  • What if? If the patient had severe liver failure, Ringer's Lactate would be contraindicated or used with extreme caution. The failing liver cannot metabolize lactate, leading to its accumulation and worsening acidosis. In such a case, Normal Saline or another crystalloid might be preferred.
How to Approach the Question
  • First, recognize that this is a factual recall question with a negative framing, indicated by the word 'EXCEPT'.
  • The goal is to identify the one substance listed that is NOT a component of standard Ringer's Lactate solution.
  • Recall the composition of Ringer's Lactate (also known as Hartmann's solution). The key components are Sodium, Potassium, Calcium, Chloride, and Lactate.
  • Evaluate each option against this list.
  • Chloride is a component.
  • Sodium is a component.
Concept Tested & Keywords
  • Concept Tested: Composition of Intravenous Fluids
  • Stem keywords: Ringer's lactate solution, constituents
  • Lead-in keywords: EXCEPT
  • Negative lead-in flag: Question is negatively framed (EXCEPT)

Question ID

QsrUDR5p1Wmz4G7NiN-ZCX

Reference Book

E6 Medicine Davidson Principles Practice 24e p. 373-375

E6 Nursing Brunner Adult Health 3SA Vol 1 Part 1 p. 142-144

E6 Gynecology Williams p. 51-74

Practise the full DSSSB -28 August 2019 (Shift-2)

Attempt every question from this paper in a timed mock, then review the full solution for each one.

More Fluid, electrolytes & Acid-base balances Questions

More DSSSB -28 August 2019 (Shift-2) Questions