Peg cells are seen in the?

Appeared in: AIIMS Patna NO - 2020

Explanation

Peg cells are non-ciliated, secretory cells located in the mucosal lining of the Fallopian tubes (oviducts).
They are interspersed between the ciliated columnar cells that are responsible for propelling the ovum.
The primary function of Peg cells is to secrete a nutrient-rich fluid that nourishes the ovum, spermatozoa, and the early embryo.
This secretion also facilitates sperm capacitation, a crucial step for fertilization.

Option A: The intestine is lined with simple columnar epithelium containing enterocytes (for absorption) and goblet cells (for mucus secretion), not Peg cells.
Option C: The stomach's mucosal lining contains specialized cells such as parietal cells (HCl), chief cells (pepsinogen), and mucous neck cells, but not Peg cells.
Option D: The vagina is lined by a protective, non-keratinized stratified squamous epithelium, which is structurally different and does not contain secretory Peg cells.

Clinical Relevance

Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Histology of the Fallopian Tube as background academic context rather than a clinical decision trigger.
The secretions from Peg cells are vital for creating a suitable environment for fertilization and early embryonic development. Their proper function is essential for fertility.
Dysfunction of Peg cells or altered secretions can contribute to infertility or increase the risk of an ectopic pregnancy, where the embryo implants outside the uterus, most commonly in the Fallopian tube.
What if the question asked about cells that move the ovum? The answer would be the ciliated cells of the Fallopian tube, which work in concert with Peg cells to ensure successful transport and development.

How to Approach the Question

This is a factual recall question based on histology.
Identify the key term in the question: 'Peg cells'.
Access your knowledge of the cellular anatomy of different organs, particularly the female reproductive system.
Recall that the Fallopian tube epithelium is unique in having both ciliated cells for transport and secretory (Peg) cells for nourishment.
Systematically eliminate the other options by recalling the characteristic cell types of the intestine (enterocytes, goblet cells), stomach (parietal, chief cells), and vagina (stratified squamous epithelium).

Concept Tested & Keywords

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E6 Histology Inderbir 11e pp. 121-123, 128-130

Practise the full AIIMS Patna NO - 2020

Attempt every question from this paper in a timed mock, then review the full solution for each one.