Match List – I with List – II and select correct answer using the code given below: List – I (Hormone Type) A. Thyrotrophs B. Gonadotrophs C. Corticotrophs D. Lactotrophs

List – II (Specific Hormone)

1. Follicle stimulating hormone and LH
2. Prolactin
3. TSH
4. ACTH

1. A

   A-3, B-1, C-4, D-2

2. B

   A-2, B-4, C-3, D-1

3. C

   A-4, B-2, C-1, D-3

4. D

   A-1, B-3, C-2, D-4

Appeared in: UPPSC 2022

Explanation

• The question tests knowledge of the specific hormones produced by different cell types in the anterior pituitary gland.
• Thyrotrophs (A) are correctly matched with TSH (3), as their primary function is to secrete Thyroid-Stimulating Hormone.
• Gonadotrophs (B) are correctly matched with Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH) (1), which are the two main gonadotropins.
• Corticotrophs (C) are correctly matched with ACTH (4), as they produce Adrenocorticotropic Hormone.
• Lactotrophs (D) are correctly matched with Prolactin (2), the hormone responsible for lactation.

Why Other Options Were Wrong

• Option B: This option incorrectly pairs Thyrotrophs (A) with Prolactin (2), Corticotrophs (C) with TSH (3), and Lactotrophs (D) with FSH/LH (1). Each of these pairings is physiologically incorrect.
• Option C: This option incorrectly pairs Thyrotrophs (A) with ACTH (4), Gonadotrophs (B) with Prolactin (2), Corticotrophs (C) with FSH/LH (1), and Lactotrophs (D) with TSH (3). All pairings are incorrect.
• Option D: This option incorrectly pairs Thyrotrophs (A) with FSH/LH (1), Gonadotrophs (B) with TSH (3), Corticotrophs (C) with Prolactin (2), and Lactotrophs (D) with ACTH (4). All pairings are incorrect.

Related Visual

Clinical Relevance

• Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Hormones of the Anterior Pituitary Gland as background academic context rather than a clinical decision trigger.
• Understanding which cells produce which hormones is fundamental to diagnosing and managing endocrine disorders. For example, a pituitary adenoma (tumor) is often functional, meaning it overproduces a specific hormone. Identifying the symptoms helps localize which cell type is affected.
• A tumor of the lactotrophs (prolactinoma) can cause hyperprolactinemia, leading to infertility, menstrual irregularities in women, and decreased libido in men.
• A tumor of the corticotrophs leads to Cushing's disease (excess ACTH), causing symptoms like weight gain, hypertension, and muscle weakness.

How to Approach the Question

• First, identify the question type. This is a 'Match the Following' question, which tests direct recall of factual relationships.
• Read both lists carefully. List I contains cell types from the anterior pituitary. List II contains hormones.
• Try to match one item from List I that you are confident about. For example, 'Lactotrophs' is strongly associated with lactation, and therefore 'Prolactin'. So, D matches with 2.
• Check the given options. Only option A has the D-2 pairing. This strongly suggests A is the correct answer.
• To confirm, verify the other matches in option A: A-3 (Thyrotrophs -> TSH), B-1 (Gonadotrophs -> FSH/LH), C-4 (Corticotrophs -> ACTH). All these pairings are correct.
• Select the option that contains all the correct pairings.

Concept Tested & Keywords

• Concept Tested: Hormones of the Anterior Pituitary Gland
• Stem keywords: Thyrotrophs, Gonadotrophs, Corticotrophs, Lactotrophs, Follicle stimulating hormone, LH, Prolactin, TSH
• Lead-in keywords: Match List, select correct answer
• Negative lead-in flag: false

Question ID

Q9AAAbAQDIyen6Wt-UaDqi

Copy ID

Reference Book

E6 Physiology Ganong 27e Vol 1 Part 2 pp. 115-117, 103-105

E6 Histology Inderbir 11e p. 136-138