NORCET 5 Prelims - Sept 2023 (Shift-1)
Medical & Surgical Nursing
Hard

A patient comes in the ED with hematemesis and mild splenomegaly. What would be the possible cause?

Appeared in: NORCET 5 Prelims - Sept 2023 (Shift-1)

Explanation

  • The combination of hematemesis (vomiting blood) and splenomegaly (enlarged spleen) is a classic presentation of portal hypertension.
  • Esophageal varices are dilated submucosal veins in the esophagus that occur in patients with portal hypertension, most commonly due to liver cirrhosis.
  • Portal hypertension causes blood to be shunted to the esophageal veins, leading to varices, and also causes congestive splenomegaly.
  • Rupture and bleeding from these varices is a life-threatening emergency that presents as hematemesis.

Why Other Options Were Wrong

  • Option A: While gastritis can cause hematemesis from inflammation of the stomach lining, it does not cause splenomegaly. The presence of both symptoms makes another diagnosis more likely.
  • Option B: Pneumonia is a lung infection and is not associated with either hematemesis or splenomegaly. Patients may have hemoptysis (coughing blood), which is different from vomiting blood.
  • Option D: Leukemia can cause splenomegaly and can lead to bleeding due to thrombocytopenia. However, it is a less common cause of acute, significant hematemesis compared to ruptured varices.

Related Visual

An illustration showing the pathophysiology of portal hypertension. It should depict the liver, portal vein, spleen, and esophagus. Arrows should indicate the normal flow of blo...
Clinical Relevance
  • Nursing practice connection: Use the key finding related to Differential diagnosis of upper GI bleeding with splenomegaly to guide bedside assessment, documentation, and the next nursing action.
  • Recognizing the link between hematemesis and splenomegaly is critical for nurses to anticipate a diagnosis of esophageal varices, a life-threatening emergency requiring immediate intervention.
  • Nursing priorities for a patient with suspected variceal bleeding include securing IV access (two large-bore cannulas), monitoring for hypovolemic shock, and preparing for emergency endoscopy and potential balloon tamponade.
  • What if? If the patient had hematemesis but no splenomegaly and a history of heavy NSAID use, the most likely cause would shift from esophageal varices to gastritis or a peptic ulcer.
How to Approach the Question
  • First, identify the key signs and symptoms in the clinical scenario: hematemesis and mild splenomegaly.
  • Consider the pathophysiology of each symptom. Hematemesis indicates upper GI bleeding. Splenomegaly indicates a systemic issue like portal hypertension, infection, or a hematologic disorder.
  • Evaluate each option to see which one provides a unified explanation for BOTH symptoms.
  • Option A (Gastritis) explains hematemesis but not splenomegaly. Option B (Pneumonia) explains neither. Option D (Leukemia) explains splenomegaly but is a less common cause of acute hematemesis.
  • Recognize that Esophageal Varices, caused by portal hypertension, is the only option that directly links upper GI bleeding (from variceal rupture) with splenomegaly (from venous congestion).
  • Therefore, select the option that best explains the complete clinical picture.
Concept Tested & Keywords
  • Concept Tested: Differential diagnosis of upper GI bleeding with splenomegaly.
  • Stem keywords: hematemesis, mild splenomegaly, ED
  • Lead-in keywords: possible cause
  • Clinical cues: The combination of hematemesis and splenomegaly is a key clinical pairing that points towards portal hypertension.

Question ID

Q9HRdC3v2JFJ5VspXEFIIZ

Reference Book

E6 Pathology- ROBBINS & COTRAN PATHOLOGIC BASIS OF DISEASE 10TH Ed p. 761-763

E6 Medicine Harrison 22e Part 2 p. 617-619

E6 Nelson Textbook of Pediatrics(2024) — Volume 2 p. 289-291

Practise the full NORCET 5 Prelims - Sept 2023 (Shift-1)

Attempt every question from this paper in a timed mock, then review the full solution for each one.

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