Which of the following substance is an enhancer of iron absorption?
Appeared in: NORCET 5 Prelims - Sept 2023 (Shift-2)
Explanation
Lemon is a citrus fruit rich in Vitamin C (ascorbic acid), a well-documented enhancer of iron absorption.
Vitamin C facilitates the absorption of non-heme iron (from plant sources) by reducing it from the ferric (Fe³⁺) state to the more soluble and absorbable ferrous (Fe²⁺) state.
The acidic environment created by lemon juice in the stomach also helps to keep iron in a soluble form, preventing the formation of insoluble iron compounds.
Why Other Options Were Wrong
Option A: Coffee contains compounds called polyphenols and tannins. These substances bind to iron in the digestive tract, forming insoluble complexes that the body cannot absorb, thereby inhibiting iron uptake.
Option C: Milk and other dairy products contain high levels of calcium. Calcium competes with iron for the same absorption pathways in the intestine, leading to a significant reduction in iron absorption.
Option D: Water is neutral and does not contain substances that either significantly enhance or inhibit iron absorption. While it's important for hydration and can be used to take supplements, it does not have the enhancing effect of Vitamin C.
Related Visual
Visual 1: Diagram - A simple flowchart showing dietary ferric iron (Fe³⁺) being converted to absorbable ferrous iron (Fe²⁺) in the presence of Vitamin C from a lemon, leading to increased absorption in the intestine.
Visual 2: Infographic - A chart listing common enhancers (Vitamin C, meat/fish) and inhibitors (calcium, phytates, polyphenols) of iron absorption with food examples for each.
Clinical Relevance
Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Factors affecting iron absorption as background academic context rather than a clinical decision trigger.
Nurses must educate patients with iron-deficiency anemia on how to maximize the effectiveness of their oral iron supplements.
Instructing patients to take iron tablets with a glass of orange or lemon juice and to avoid taking them with milk, tea, or coffee can dramatically improve therapeutic outcomes.
What if? If a patient experiences significant stomach upset when taking iron with juice on an empty stomach, they can take it with a small meal. However, the nurse should explain that this reduces absorption, and they should still avoid dairy, coffee, or tea with that meal.
How to Approach the Question
First, identify the core of the question: it asks for a substance that enhances (improves) iron absorption.
Next, recall or look up the key factors that influence iron absorption. The most well-known enhancer is Vitamin C (ascorbic acid), and common inhibitors include calcium and tannins/polyphenols.
Evaluate each option against this knowledge. Coffee contains tannins. Milk contains calcium. Water is neutral.
Identify that Lemon is a primary source of Vitamin C and citric acid, both of which promote iron absorption.
Conclude that Lemon is the only enhancer among the choices.
Concept Tested & Keywords
Concept Tested: Factors affecting iron absorption
Stem keywords: enhancer, iron absorption
Lead-in keywords: Which
Negative lead-in flag: false
Question ID
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Practise the full NORCET 5 Prelims - Sept 2023 (Shift-2)
Attempt every question from this paper in a timed mock, then review the full solution for each one.