ISRO 2024
Applied Physiology
Easy

Which of the following organelles is called the "suicidal bag"?

Appeared in: ISRO 2024

Explanation

  • Lysosomes are cellular organelles that contain powerful digestive (hydrolytic) enzymes.
  • They are known as 'suicidal bags' because if the lysosomal membrane ruptures, these enzymes are released into the cell's cytoplasm.
  • This release triggers autolysis, a process where the enzymes digest the cell's own components, leading to cell death.

Why Other Options Were Wrong

  • Option A: This is incorrect. Mitochondria are known as the 'powerhouse' of the cell, not the 'suicidal bag'.
  • Option B: This is incorrect. The Endoplasmic Reticulum is a network involved in protein and lipid synthesis and transport.
  • Option D: This is incorrect. Ribosomes are known as the 'protein factories' of the cell.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Functions and nicknames of cellular organelles as background academic context rather than a clinical decision trigger.
  • Understanding lysosomal function is critical for diagnosing and managing lysosomal storage diseases like Tay-Sachs or Gaucher disease, where enzyme deficiencies cause harmful accumulations within cells.
  • What if? If a cell is infected with a virus, the cell can intentionally trigger lysosomal rupture (a part of apoptosis or programmed cell death) as a defense mechanism to destroy itself and prevent the virus from replicating and spreading to other cells.
How to Approach the Question
  • This is a factual recall question testing knowledge of basic cell biology.
  • The key phrase is 'suicidal bag.' This is a specific nickname tied to the function of one organelle.
  • Mentally review the common nicknames for the organelles listed in the options.
  • Mitochondria is the 'powerhouse'.
  • Ribosome is the 'protein factory'.
  • Endoplasmic Reticulum is the 'transport network'.
Concept Tested & Keywords
  • Concept Tested: Functions and nicknames of cellular organelles
  • Stem keywords: organelles, suicidal bag
  • Lead-in keywords: Which
  • Negative lead-in flag: false

Question ID

QA3TBPiPapEQulZj6LtY7M

Reference Book

E6 Physiology Essentials Sembulingam 10e Part 1 p. 31-33

E6 Anatomy Applied Ashalatha 4e p. 59-61

Practise the full ISRO 2024

Attempt every question from this paper in a timed mock, then review the full solution for each one.

Which of the following organelles is called the "suicidal bag"? - ISRO 2024 | NPrep