DSSSB 14 August 2024
Medical & Surgical Nursing
Easy

Which of the following diseases is characterised by Charcot's triad?

Appeared in: DSSSB 14 August 2024

Explanation

  • Multiple sclerosis (MS) is the correct answer as it is classically associated with Charcot's neurologic triad.
  • This triad results from demyelination in the cerebellum and brainstem, which are areas of the brain responsible for coordination, balance, and control of eye and speech muscles.
  • The components of the triad are nystagmus (involuntary eye movements), intention tremor (tremor during purposeful movement), and scanning speech (slow, disjointed speech).
  • The presence of these three signs together is a strong indicator of MS, although they may not all be present in every patient.

Why Other Options Were Wrong

  • Option B: Parkinson's disease is characterized by a different set of classic symptoms, often called the Parkinsonian triad: resting tremor, rigidity, and bradykinesia (slowness of movement).
  • Option C: Guillain-Barré syndrome (GBS) is primarily known for rapidly ascending symmetric muscle weakness or paralysis and areflexia (absence of deep tendon reflexes).
  • Option D: Myasthenia gravis is an autoimmune disorder of the neuromuscular junction, leading to fluctuating, fatigable muscle weakness. Its hallmark signs are ptosis (drooping eyelids) and diplopia (double vision), which worsen with activity.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Identification of classic signs and triads associated with major neurological disorders as background academic context rather than a clinical decision trigger.
  • Nurses caring for patients with Multiple Sclerosis must implement safety precautions due to ataxia and intention tremors, such as ensuring a clutter-free environment to prevent falls.
  • Communication can be challenging due to scanning speech (dysarthria). Nurses should be patient, allow ample time for the patient to respond, and consider using communication aids.
  • It is crucial to distinguish between Charcot's neurologic triad (for MS) and Charcot's biliary triad (fever, jaundice, right upper quadrant pain), which indicates ascending cholangitis, a completely different and acute condition requiring urgent medical intervention.
How to Approach the Question
  • First, identify the key term in the question, which is 'Charcot's triad'.
  • This is a factual recall question. Access your knowledge of classic signs and symptoms associated with major neurological diseases.
  • Recall the three components of Charcot's neurologic triad: nystagmus, intention tremor, and scanning speech.
  • Systematically evaluate each option to see which disease matches this triad.
  • Eliminate options associated with different classic signs: Parkinson's (resting tremor, rigidity, bradykinesia), GBS (ascending paralysis), and Myasthenia Gravis (fatigable weakness, ptosis).
  • Confirm that Multiple Sclerosis is the disease classically linked to Charcot's neurologic triad.
Concept Tested & Keywords
  • Concept Tested: Identification of classic signs and triads associated with major neurological disorders.
  • Stem keywords: Charcot's triad, disease
  • Lead-in keywords: characterised by
  • Negative lead-in flag: false

Question ID

QFHWAhq3mXOrclcq620sX1

Reference Book

E6 Textbook of Biochemistry for medical StudentsDM Vasudevan Part 2 — Subpart B (pp 240-463 of 478) p. 128-130

E6 Robert Boland, Marcia L. Verduin - Kaplan and Sadock's Comprehensive Text of Psychiatry-Wolters Kluwer Health (2024) (pp 1-16525 of 16525) p. 1591-1593

E6 Nelson Textbook of Pediatrics(2024) — Volume 2 p. 1602-1604

Practise the full DSSSB 14 August 2024

Attempt every question from this paper in a timed mock, then review the full solution for each one.

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