KPSC Staff Nurse - 2016
Applied Physiology
Easy

What is the primary action of insulin in the body?

Appeared in: KPSC Staff Nurse - 2016

Explanation

  • The primary and most immediate action of insulin is to facilitate the transport of glucose from the bloodstream into cells, especially muscle and adipose tissue.
  • Insulin binds to its receptor on the cell surface, which initiates a signal to move glucose transporters (specifically GLUT4) to the cell membrane.
  • These transporters act as channels, allowing glucose to enter the cell, thereby lowering the concentration of glucose in the blood.
  • This process is crucial for maintaining normal blood glucose levels, particularly after a meal when glucose absorption from the gut is high.

Why Other Options Were Wrong

  • Option B: Insulin actively inhibits or suppresses gluconeogenesis, which is the process of creating new glucose in the liver. This action helps to lower blood sugar, not raise it.
  • Option C: Insulin is the hormone produced and secreted by pancreatic beta cells; it does not stimulate them. The primary stimulator for insulin release is high blood glucose.
  • Option D: Insulin does not have a primary role in altering the absorption of glucose from the intestines.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Primary physiological action of insulin as background academic context rather than a clinical decision trigger.
  • Understanding insulin's primary action is fundamental for nurses managing patients with diabetes mellitus. Administering insulin mimics this natural process to control hyperglycemia.
  • A critical nursing responsibility is monitoring for hypoglycemia (low blood sugar) after insulin administration. Because insulin efficiently moves glucose into cells, it can sometimes lower blood glucose levels too much, which is a medical emergency.
  • Patient education is key. Nurses must teach patients why they need insulin, how it works to lower their blood sugar, and the signs of hypoglycemia to watch for.
How to Approach the Question
  • First, identify the core of the question. It asks for the 'primary action' of insulin, meaning its main and most direct effect.
  • Think about the main problem in diabetes: high blood sugar. Insulin is the hormone that corrects this. Therefore, its primary action must be to lower blood sugar.
  • Analyze the options to see which one describes a mechanism for lowering blood sugar.
  • Option A: 'Enhances the transport of glucose across cell walls.' This describes moving sugar out of the blood and into cells, which would lower blood sugar. This is a strong candidate.
  • Option B: 'Aids in the process of gluconeogenesis.' Gluconeogenesis means creating new glucose. This would raise blood sugar, which is the opposite of what insulin does.
  • Option C: 'Stimulates the pancreatic beta cells.' Beta cells produce insulin. Insulin is the product, not the stimulus. High glucose is the stimulus.
Concept Tested & Keywords
  • Concept Tested: Primary physiological action of insulin
  • Stem keywords: primary action, insulin, body
  • Lead-in keywords: What is
  • Negative lead-in flag: false

Question ID

Qu9ROVftOjnnikUOuVXt5Z

Reference Book

E6 Physiology Guyton 4SAE Part 3 p. 2-4

E6 Physiology Essentials Sembulingam 10e Part 2 p. 63-65

Practise the full KPSC Staff Nurse - 2016

Attempt every question from this paper in a timed mock, then review the full solution for each one.