AIIMS Patna NO - 2020
Applied Physiology
Easy
What is the correct sequence of mitosis?
Appeared in: AIIMS Patna NO - 2020
Explanation
- Mitosis is the process of somatic cell division that occurs in a specific, ordered sequence to ensure accurate distribution of genetic material.
- The correct order of the four main stages is Prophase → Metaphase → Anaphase → Telophase.
- During Prophase, chromosomes condense and become visible.
- In Metaphase, chromosomes align at the cell's equator.
- During Anaphase, sister chromatids separate and move to opposite poles.
- In Telophase, two new nuclei form, followed by the division of the cytoplasm (cytokinesis).
Why Other Options Were Wrong
- Option B: This option starts with Anaphase, which is the third stage of mitosis. The sequence is incorrect.
- Option C: This option starts with Telophase, the final stage, and incorrectly repeats it at the end. The sequence is incorrect.
- Option D: This option starts with Metaphase, the second stage. The sequence is out of order.
Related Visual
Clinical Relevance
- Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Phases of Mitosis as background academic context rather than a clinical decision trigger.
- Understanding the normal process of mitosis helps nurses comprehend the mechanism of tissue repair and wound healing.
- Knowledge of the cell cycle is crucial for understanding cancer, which is characterized by uncontrolled cell division (mitosis). Many chemotherapeutic agents are designed to disrupt specific phases of mitosis in rapidly dividing cancer cells.
- What if the question was about meiosis? The answer would involve two rounds of division (Meiosis I and Meiosis II) and result in four haploid cells, which is different from the two diploid cells produced in mitosis.
How to Approach the Question
- First, identify the core concept of the question, which is the sequence of mitosis.
- Recall the stages of cell division. A common mnemonic for the mitotic phases is PMAT.
- P = Prophase
- M = Metaphase
- A = Anaphase
- T = Telophase
Concept Tested & Keywords
- Concept Tested: Phases of Mitosis
- Stem keywords: mitosis, sequence
- Lead-in keywords: correct
Question ID
Q6goFfFO6aanZnEao3cmZu
Reference Book
E6 Physiology Guyton 4SAE Part 1 p. 66-68
E6 Pathology-Textbook of PATHOLOGYHarsh Mohan Part 1 (1-214) p. 49-51
E6 Anatomy Applied Ashalatha 4e p. 64-66
Practise the full AIIMS Patna NO - 2020
Attempt every question from this paper in a timed mock, then review the full solution for each one.
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