CGHS SSC - 2018
Pharmacology
Easy

The drug used for mood stabilization is?

Appeared in: CGHS SSC - 2018

Explanation

  • Lithium carbonate is a first-line mood-stabilizing agent, primarily indicated for the treatment of bipolar disorder.
  • It is effective in managing acute manic episodes and as a long-term maintenance therapy to prevent the recurrence of both manic and depressive episodes.
  • Lithium works by altering sodium ion transport in nerve cells, which in turn modulates the metabolism of neurotransmitters like catecholamines and serotonin.
  • Due to its narrow therapeutic range (0.6-1.2 mEq/L), regular monitoring of serum levels is critical to prevent toxicity.

Why Other Options Were Wrong

  • Option A: Chlorpheniramine is an antihistamine, not a mood stabilizer. Its primary use is to relieve symptoms of allergies.
  • Option B: Alcohol is a central nervous system (CNS) depressant. While it affects mood, it is a substance of abuse and not a prescribed medication for mood stabilization. Its use can exacerbate mood disorders.
  • Option C: Penicillin is an antibiotic from the beta-lactam class used to treat bacterial infections. It has no psychiatric or mood-stabilizing effects.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: Knowing Pharmacological treatment for mood disorders, specifically the identification of a mood-stabilizing agent helps nurses interpret findings accurately and avoid errors in routine assessment, medication administration, and patient teaching.
  • Nurses play a vital role in educating patients about the importance of regular blood tests to monitor lithium levels due to its narrow therapeutic index.
  • Patient teaching must emphasize maintaining a consistent sodium and fluid intake (e.g., 2-3 liters per day) because dehydration or low sodium can cause lithium retention and toxicity.
  • It is a critical nursing responsibility to instruct patients and their families to recognize and immediately report early signs of toxicity, such as coarse tremors, vomiting, diarrhea, and confusion.
How to Approach the Question
  • First, identify the key therapeutic action requested in the question, which is 'mood stabilization'.
  • Next, analyze each drug option and recall its primary pharmacological class and use.
  • Classify Chlorpheniramine as an antihistamine.
  • Classify Alcohol as a CNS depressant and substance of abuse, not a therapeutic agent.
  • Classify Penicillin as an antibiotic.
  • Identify Lithium carbonate as a well-known mood stabilizer.
Concept Tested & Keywords
  • Concept Tested: Pharmacological treatment for mood disorders, specifically the identification of a mood-stabilizing agent.
  • Stem keywords: drug, mood stabilization
  • Lead-in keywords: is
  • Negative lead-in flag: false

Question ID

QkYSPjYG9DMVRRsa_l69B7

Reference Book

E6 Kaplan Sadock's Synopsis of Psychiatry-2022 (pp 1-3768 of 3768) p. 2046-2048

E6 Pharmacology KD Tripathi Essentials 9e Part 2 p. 118-120

E6 Pharmacology Nursing Lilley 11e Part 1 p. 272-274

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The drug used for mood stabilization is? - CGHS SSC - 2018 | NPrep