Haryana CHO -2023
Applied Microbiology & Infection control
Easy

Specimen required for the diagnosis of Swine Flu is:

Appeared in: Haryana CHO -2023

Explanation

  • Swine Flu (Influenza A H1N1) is a viral infection that primarily affects the upper respiratory tract.
  • The highest concentration of the virus, and therefore the highest diagnostic yield, is found in respiratory secretions.
  • A throat swab allows for the collection of these secretions for analysis.
  • The gold standard diagnostic test, Real-Time Reverse Transcription Polymerase Chain Reaction (rRT-PCR), is performed on respiratory samples to detect viral RNA.

Why Other Options Were Wrong

  • Option A: Influenza is a respiratory virus and is not typically present or shed in urine, making it an unsuitable specimen for diagnosis.
  • Option B: Blood is not used for the acute diagnosis of influenza virus. Viremia (virus in the blood) is uncommon. Blood is used for serology to detect antibodies, which appear later in the infection, not for detecting the virus itself during the acute phase.
  • Option D: Stool is not a suitable specimen as the influenza virus primarily replicates in the respiratory system, not the gastrointestinal tract. While some patients may have GI symptoms, viral shedding in stool is not a reliable diagnostic marker.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: Use the key finding related to Specimen collection for Swine Flu (H1N1) diagnosis to guide bedside assessment, documentation, and the next nursing action.
  • Accurate and timely diagnosis of Swine Flu through proper specimen collection is crucial for initiating antiviral treatment, implementing infection control measures, and preventing community spread.
  • Nurses must use appropriate Personal Protective Equipment (PPE), including an N95 mask, gown, gloves, and eye protection, during specimen collection to prevent aerosol transmission and protect themselves and others.
  • What if? If a patient cannot tolerate a throat swab (e.g., due to a strong gag reflex or being a young child), a nasopharyngeal or nasal swab is an equally acceptable and effective alternative specimen from the upper respiratory tract.
How to Approach the Question
  • First, identify the disease mentioned in the question: "Swine Flu" (Influenza A H1N1).
  • Recall or deduce the nature of this disease. Influenza is a well-known respiratory infection.
  • Consider the primary site of infection for a respiratory disease, which is the respiratory tract (nose, throat, lungs).
  • Evaluate the given options based on this understanding. The specimen must be collected from a site where the pathogen is most likely to be present in high quantities.
  • Eliminate options that are not related to the respiratory system (Urine, Stool) or are used for different diagnostic purposes (Blood for serology).
  • Select the option that represents a sample from the respiratory tract, which is the Throat swab.
Concept Tested & Keywords
  • Concept Tested: Specimen collection for Swine Flu (H1N1) diagnosis
  • Stem keywords: Specimen required, diagnosis, Swine Flu
  • Lead-in keywords: is
  • Negative lead-in flag: false

Question ID

QFO88qu4MBfTg5hswQn1FX

Reference Book

E6 Parks TextBook of Preventive & Social Medicine part 1 — Subpart A (pp 26-201 of 604) p. 160-162

E6 Nelson Textbook of Pediatrics(2024) — Volume 1 p. 2029-2031

Practise the full Haryana CHO -2023

Attempt every question from this paper in a timed mock, then review the full solution for each one.