Uttarakhand CHO - 2021
Microbiology
Easy

Impetigo is caused by which pathogen?

Appeared in: Uttarakhand CHO - 2021

Explanation

  • Impetigo is a superficial bacterial skin infection most commonly caused by Staphylococcus aureus.
  • It can also be caused by Streptococcus pyogenes (Group A Streptococcus), or a combination of both.
  • S. aureus is particularly responsible for the bullous form of impetigo, which is characterized by large blisters, due to the production of exfoliative toxins.
  • The non-bullous form, which is more common, presents with characteristic honey-colored crusts and can be caused by either S. aureus or S. pyogenes.

Why Other Options Were Wrong

  • Option B: Klebsiella species are gram-negative bacteria that typically cause nosocomial infections like pneumonia and urinary tract infections, not superficial skin infections like impetigo.
  • Option C: Mycobacterium is a genus of bacteria responsible for chronic granulomatous diseases, primarily tuberculosis and leprosy.
  • Option D: E. coli is a gram-negative bacterium that is a major cause of urinary tract infections and various gastrointestinal diseases, but not impetigo.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Etiology of Impetigo as background academic context rather than a clinical decision trigger.
  • Correctly identifying the likely pathogen is crucial for selecting the appropriate antibiotic therapy and preventing the spread of this highly contagious infection.
  • Nurses play a key role in educating patients and families about hygiene measures, such as handwashing and not sharing personal items, to control transmission in homes and schools.
  • Recognizing the signs of impetigo is important for early intervention to prevent complications like cellulitis or post-streptococcal glomerulonephritis (though rare).
How to Approach the Question
  • First, identify the key term in the question, which is 'Impetigo'.
  • This is a factual recall question. Access your knowledge about common skin infections and their causative agents.
  • Evaluate each option. Recall that Staphylococcus aureus and Streptococcus are the most common bacteria causing superficial skin infections.
  • Consider the other options: Klebsiella, Mycobacterium, and E. coli. Associate these with their typical infections (pneumonia/UTI, TB/leprosy, and UTI/GI infections, respectively).
  • Eliminate the incorrect options based on this knowledge, which leaves Staphylococcus aureus as the most plausible cause among the choices.
  • Confirm the answer. Staphylococcus aureus is the leading cause of impetigo.
Concept Tested & Keywords
  • Concept Tested: Etiology of Impetigo
  • Stem keywords: Impetigo, pathogen, caused by
  • Lead-in keywords: BEST, MOST RELEVANT CLUE
  • Negative lead-in flag: false

Question ID

QcZqvtpZYSJLRmuLTN7Cs7

Reference Book

E6 Medicine Harrison 22e Part 1 pp. 430-432, 1251-1253

E6 Nelson Textbook of Pediatrics(2024) — Volume 1 p. 1711-1713

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