Identify the incorrect pair among the following:

Appeared in: OSSSC Nursing Officer-2021

Explanation

The DPT vaccine protects against Diphtheria, Pertussis (whooping cough), and Tetanus.
The correct route of administration for the DPT vaccine is Intramuscular (IM), not Subcutaneous (SC).
It is typically injected into the anterolateral aspect of the thigh in infants.
Administering DPT subcutaneously is incorrect and can lead to severe local reactions, such as sterile abscesses, because the vaccine contains an aluminum adjuvant which is irritant to fatty tissue.

Option A: This option represents a correct pair. The BCG (Bacillus Calmette-Guérin) vaccine is given to protect against Tuberculosis (TB) via the intradermal route.
Option C: This option represents a correct pair. The MMR vaccine protects against Measles, Mumps, and Rubella and is administered via the subcutaneous (S/C) route.
Option D: This option represents a correct pair. The Oral Polio Vaccine (OPV) protects against Poliomyelitis and is administered orally.

Clinical Relevance

Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Vaccine Administration Routes as background academic context rather than a clinical decision trigger.
Using the correct administration route is critical for vaccine efficacy and patient safety. An incorrect route can lead to a reduced immune response, vaccine failure, or adverse local reactions.
For example, giving BCG subcutaneously instead of intradermally can cause a large abscess and lymphadenitis. Giving DPT subcutaneously can cause sterile abscesses due to the aluminum adjuvant.
Nurses must be vigilant in checking the vaccine type and its prescribed route before administration as part of the rights of medication administration.

How to Approach the Question

First, recognize that the question asks you to identify the incorrect pair from the list.
Break down each option into its three components: Vaccine name, Disease it prevents, and Route of administration.
Systematically evaluate each component of every option for accuracy based on your knowledge of the national immunization schedule.
For Option A: BCG for TB via Intradermal route. This is correct.
For Option B: DPT for Pertussis via Subcutaneous route. DPT is for Pertussis, but the route is Intramuscular (IM), not Subcutaneous (SC). This makes the pair incorrect.
For Option C: MMR for Rubella via Subcutaneous route. This is correct.

Concept Tested & Keywords

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E6 Parks TextBook of Preventive & Social Medicine part 1 — Subpart C (pp 404-604 of 604) p. 126-128

E6 Comprehensive Textbook of Community Health Nursing for BSc Nursing Students Part 2 — Subpart B (pp 276-535 of 550) p. 232-234

Practise the full OSSSC Nursing Officer-2021

Attempt every question from this paper in a timed mock, then review the full solution for each one.