Identify the incorrect options about Antra injection?

NORCET 3 - 2022 (Shift-2)

Pharmacology

Medium

Appeared in: NORCET 3 - 2022 (Shift-2)

Explanation

The statement that Antra injection can be given to lactating mothers is considered incorrect because it is an oversimplification.
Progestin-only injectables like DMPA (Antra) are contraindicated for women who are breastfeeding a baby less than 6 weeks old.
This waiting period is crucial to avoid any potential effects on the newborn and to ensure the mother's lactation is well-established.
While it is a suitable contraceptive method for lactating mothers after 6 weeks postpartum, the unqualified statement makes it factually incorrect in an examination context.

Option A: This is a correct statement. Antra is a widely used brand name for Depot Medroxyprogesterone Acetate (DMPA), which is a progestin hormone.
Option B: This is a correct statement. The standard and effective dosing schedule for the 150 mg DMPA injection is once every 3 months (or every 12-13 weeks).
Option C: This is a correct statement. DMPA is formulated to be administered as a deep intramuscular (IM) injection to create a depot from which the hormone is slowly released.

Visual 1: Diagram - A timeline showing the recommended start times for DMPA injection in postpartum women, highlighting the 6-week delay for breastfeeding mothers.
Visual 2: Image - A photo of the Antra (DMPA) vial and syringe to help students visually associate the drug with its form.

Clinical Relevance

Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Pharmacology of Injectable Contraceptives as background academic context rather than a clinical decision trigger.
A critical nursing responsibility is screening patients for contraindications. For postpartum mothers, asking about the date of delivery and breastfeeding status is essential before administering DMPA.
Patient counseling must include the precise injection schedule (every 3 months) and the importance of returning on time to maintain contraceptive efficacy.
What if? If a breastfeeding mother requests a contraceptive at her 2-week postpartum check-up, the nurse should explain that DMPA is not recommended yet and discuss alternative methods (like progestin-only pills or barrier methods) until she reaches the 6-week mark.

How to Approach the Question

First, read the question carefully and note the keyword 'incorrect'. This means you are looking for the false statement among the options.
Evaluate each option based on your knowledge of the drug 'Antra injection' (DMPA).
Option A: Recall the composition. Antra is DMPA, which contains medroxyprogesterone. This is true.
Option B: Recall the schedule. DMPA is given every 3 months. This is true.
Option C: Recall the route. DMPA is an IM injection. This is true.
Option D: Recall its use in special populations. Think if there are any restrictions for lactating mothers. There is a key restriction in the first 6 weeks postpartum. This makes the general statement 'can be given' incorrect because of this important exception.

Concept Tested & Keywords

Concept Tested: Pharmacology of Injectable Contraceptives
Stem keywords: Antra injection, medroxyprogesterone, intramuscular, lactating mothers
Lead-in keywords: incorrect
Negative lead-in flag: The question asks to identify the INCORRECT statement.

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