UPRVUNL - 2021
Child Health Nursing (Pediatrics)
Easy

Which of the following is a treatment of choice for a child with lead poisoning?

Appeared in: UPRVUNL - 2021

Explanation

  • Chelating agents are the definitive treatment for moderate to severe lead poisoning.
  • These drugs bind to lead in the blood and tissues, forming a stable, non-toxic complex.
  • This complex is then excreted from the body, primarily through the kidneys, which effectively lowers the body's total lead burden.
  • Common agents include Succimer (DMSA), Calcium Disodium Edetate (CaNa₂EDTA), and Dimercaprol (BAL), chosen based on the severity of poisoning.

Why Other Options Were Wrong

  • Option A: Gastric lavage only removes contents from the stomach and is ineffective once lead has been absorbed into the bloodstream. It does not treat systemic toxicity.
  • Option B: Activated charcoal does not adsorb heavy metals like lead, iron, or lithium, making it an ineffective treatment for this type of poisoning.
  • Option C: Antiemetics only provide symptomatic relief for nausea and vomiting; they do not address the root cause of the illness by removing the toxic lead from the body.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: Prioritize focused assessment, early escalation, and real-time monitoring when managing Pharmacological management of pediatric lead poisoning in acute care settings.
  • A critical nursing responsibility during chelation therapy is ensuring the child maintains adequate hydration. This protects the kidneys from injury (nephrotoxicity) as they work to excrete the lead-chelate complex.
  • Patient and family education is paramount. Nurses must teach families how to identify and eliminate sources of lead in the environment (e.g., old paint, contaminated soil, certain toys) to prevent re-exposure, which is essential for long-term recovery.
  • Nurses must monitor for adverse effects of chelation, such as gastrointestinal distress, rashes, and changes in liver enzymes, and ensure follow-up blood tests are completed to track the decline in lead levels.
How to Approach the Question
  • First, identify the core question: It asks for the 'treatment of choice' for a specific condition, which is lead poisoning in a child.
  • This requires recalling the primary, most effective therapy, not just a supportive or situational measure.
  • Evaluate each option's mechanism. Does it address the root cause (systemic lead) or just a symptom/initial ingestion?
  • Analyze the distractors: 'Gastric lavage' is for recent ingestion, not absorbed poison. 'Antiemetic' treats a symptom (vomiting), not the cause. 'Activated charcoal' is known to be ineffective for heavy metals.
  • Focus on the remaining option, 'Chelating agents'. Recall that chelation is the specific chemical process used to remove heavy metals from the body.
  • Conclude that chelating agents are the only option that provides a definitive, systemic treatment for established lead poisoning.
Concept Tested & Keywords
  • Concept Tested: Pharmacological management of pediatric lead poisoning
  • Stem keywords: treatment of choice, child, lead poisoning
  • Lead-in keywords: Which
  • Clinical cues: Age/sex group narrows the expected diagnosis, intervention, or normal reference range.
  • Negative lead-in flag: false

Question ID

QpcRu6Q2hM-oRLNm5wvVuH

Reference Book

E6 Nelson Textbook of Pediatrics(2024) — Volume 2 p. 2252-2254

E6 Nelson Textbook of Pediatrics(2024) — Volume 1 p. 752-754

E6 Ghai Essential Pediatrics(pp 26-904 of 913) p. 752-754

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