MP CHO-2018
Medical & Surgical Nursing
Easy

What is the enlargement of the Thyroid Gland due to Iodine deficiency called?

Appeared in: MP CHO-2018

Explanation

  • Goitre is the medical term for the enlargement of the thyroid gland.
  • The most common cause of goitre worldwide is a deficiency of iodine in the diet.
  • Iodine is an essential component for the synthesis of thyroid hormones (T3 and T4).
  • When iodine is deficient, thyroid hormone production falls, leading to a compensatory increase in Thyroid-Stimulating Hormone (TSH) from the pituitary gland.
  • This elevated TSH level causes the thyroid gland to undergo hypertrophy (increase in cell size) and hyperplasia (increase in cell number), resulting in an enlarged gland or goitre.

Why Other Options Were Wrong

  • Option A: Cretinism is a condition of severe, irreversible physical and mental developmental delay, not just the enlargement of the thyroid gland. It is caused by untreated congenital hypothyroidism, which can result from maternal iodine deficiency.
  • Option C: Hyperthyroidism is a condition where the thyroid gland is overactive and produces an excess of thyroid hormones. Iodine deficiency typically causes hypothyroidism (underactive thyroid) or a euthyroid (normal function) state, not hyperthyroidism.
  • Option D: Graves' disease is an autoimmune disorder that is the most common cause of hyperthyroidism. It is caused by antibodies that stimulate the TSH receptor, leading to overproduction of thyroid hormones and often a goitre, but its primary cause is not iodine deficiency.

Related Visual

Visual explanation — Related Visual
Clinical Relevance
  • Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Thyroid Gland Disorders as background academic context rather than a clinical decision trigger.
  • Nurses play a crucial role in public health education regarding the importance of dietary iodine, especially through the use of iodized salt, to prevent endemic goitre.
  • During a physical assessment, a nurse should inspect and palpate the neck for any thyroid enlargement and inquire about compressive symptoms like difficulty swallowing, breathing, or voice changes.
  • What if? If a patient with an enlarged thyroid also presented with weight loss, heat intolerance, and palpitations, the nurse's primary suspicion should shift from simple iodine-deficiency goitre to a hyperthyroid state, such as Graves' disease, requiring different diagnostic tests and management.
How to Approach the Question
  • First, identify the key concepts in the question: 'enlargement of the Thyroid Gland' and the specific cause, 'Iodine deficiency'.
  • Recall the basic physiology of the thyroid gland: it needs iodine to produce thyroid hormones.
  • Consider the body's feedback loop: low hormone levels trigger the pituitary to release more TSH to stimulate the gland.
  • Evaluate the options: 'Goitre' is the general term for an enlarged thyroid. 'Cretinism' is a severe congenital condition. 'Hyperthyroidism' and 'Graves' disease' relate to an overactive thyroid, which is inconsistent with simple iodine deficiency.
  • Connect the cause (iodine deficiency) to the effect (compensatory enlargement). This directly points to goitre as the correct answer.
Concept Tested & Keywords
  • Concept Tested: Thyroid Gland Disorders
  • Stem keywords: enlargement, Thyroid Gland, Iodine deficiency
  • Lead-in keywords: What is
  • Negative lead-in flag: false

Question ID

QIZK0Gj3dH39KcVrdOWtC8

Reference Book

E6 Pathology- ROBBINS & COTRAN PATHOLOGIC BASIS OF DISEASE 10TH Ed p. 1082-1084

E6 Textbook of Biochemistry for medical StudentsDM Vasudevan Part 2 — Subpart B (pp 240-463 of 478) p. 153-155

E6 Nursing Brunner Adult Health 3SA Vol 1 Part 4 p. 25-27

Practise the full MP CHO-2018

Attempt every question from this paper in a timed mock, then review the full solution for each one.