Wermer's syndrome is considered as?

Appeared in: RRB Nsg. Superintendent 21 July 2019 (shift 1st)

Explanation

Wermer's syndrome is the established eponym for Multiple Endocrine Neoplasia type 1 (MEN I).
This is an autosomal dominant disorder, meaning an affected individual has a 50% chance of passing the condition to each child.
The classic presentation involves tumors of the Parathyroid, Pancreas, and Pituitary glands, commonly remembered by the mnemonic '3 Ps'.

Option B: MEN II, also known as MEN 2A or Sipple's syndrome, has a different constellation of tumors.
Option C: MEN IV is a more recently described and rarer syndrome with a different genetic cause and tumor profile.
Option D: MEN III is an older term for what is now classified as MEN 2B.

Visual 1: Diagram - An infographic illustrating the endocrine glands affected in MEN I (Parathyroid, Pancreas, Pituitary), MEN 2A, and MEN 2B to visually differentiate the syndromes.

Clinical Relevance

Nursing practice connection: Knowing Classification and eponyms of Multiple Endocrine Neoplasia (MEN) syndromes helps nurses interpret findings accurately and avoid errors in routine assessment, medication administration, and patient teaching.
Recognizing eponyms like Wermer's syndrome is crucial for accurate communication and understanding of a patient's diagnosis.
A diagnosis of any MEN syndrome necessitates lifelong surveillance for tumors in the associated glands, as well as genetic counseling and screening for first-degree relatives.
Nursing care involves patient education about the genetic nature of the disease, the importance of regular follow-ups, managing symptoms of hormone excess, and providing psychosocial support.

How to Approach the Question

First, identify the keyword in the question, which is 'Wermer's syndrome'.
Recognize that this is a factual recall question asking for the classification of a named syndrome.
Access your knowledge of endocrine disorders and their eponyms.
Associate 'Wermer's syndrome' with MEN type 1.
Use the '3 Ps' mnemonic (Parathyroid, Pancreas, Pituitary) to confirm the characteristics of MEN I and differentiate it from other MEN types.
Evaluate the given options and select the one that correctly matches the eponym.

Concept Tested & Keywords

Concept Tested: Classification and eponyms of Multiple Endocrine Neoplasia (MEN) syndromes.
Stem keywords: Wermer's syndrome
Lead-in keywords: is considered as

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Practise the full RRB Nsg. Superintendent 21 July 2019 (shift 1st)

Attempt every question from this paper in a timed mock, then review the full solution for each one.