Q19. Which of the following statements regarding wound healing is correct?

Appeared in: INI-CET EXAM -2026

Explanation

Wound healing is a dynamic process with three overlapping phases: Inflammation, Proliferation, and Maturation.
The proliferative phase, starting around day 3-4, is characterized by the formation of new tissue to fill the wound space.
A key event in this phase is angiogenesis, the formation of new blood vessels from pre-existing ones, which is essential for delivering oxygen and nutrients to the healing tissue.
This new vascular network, along with fibroblasts and collagen, forms the granulation tissue that fills the wound.

Option A: The exudative phase is another name for the inflammatory phase, which is the first stage of wound healing. It does not follow it.
Option B: Type III collagen, which is weaker and more disorganized, is deposited in the early proliferative phase. Stronger Type I collagen is laid down later during the remodeling phase to provide tensile strength.
Option D: The process is reversed. During the maturation/remodeling phase, stronger Type I collagen replaces the initial, weaker Type III collagen to increase the tensile strength of the scar.

Clinical Relevance

Nursing practice connection: Knowing Phases of wound healing and associated cellular events helps nurses interpret findings accurately and avoid errors in routine assessment, medication administration, and patient teaching.
Nurses assess wound healing by recognizing the signs of each phase (e.g., inflammation, granulation tissue, scar formation) to determine if healing is progressing normally.
Understanding the role of angiogenesis helps explain why conditions that impair blood flow, like diabetes or peripheral vascular disease, lead to chronic, non-healing wounds.
Knowledge of collagen types is crucial for understanding scar strength and complications like hypertrophic scarring or keloids.

How to Approach the Question

This is a factual recall question about a fundamental physiological process.
First, identify the core concept: the stages of wound healing.
Mentally review the sequence and key events of each phase: 1. Inflammation (hemostasis, cleanup), 2. Proliferation (granulation, angiogenesis, epithelialization), and 3. Maturation (remodeling, collagen conversion).
Evaluate each option against this established physiological sequence.
Option A confuses terminology for the first phase.
Options B and D incorrectly state the roles and replacement sequence of Type I and Type III collagen.

Concept Tested & Keywords

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E6 Pathology-Textbook of PATHOLOGYHarsh Mohan Part 1 (1-214) p. 135-137

E6 PATHOLOGY QUICK REVIEWBased on Harsh Mohan Textbook of PATHOLOGY p. 40-42

E6 Nursing Fundamentals Potter Perry 12e Part 6 p. 74-76

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