Match List I with List II

VACCINE	ROUTE OF ADMINISTRATION
A. Pneumococcal vaccine	I. Subcutaneous
B. Rotavirus	II. Intramuscular
C. Measles	III. Intradermal
D. BCG	IV. Oral

1. A

   A-II, B-IV, C-I, D-III

2. B

   A-I, B-III, C-IV, D-II

3. C

   A-I, B-II, C-IV, D-III

4. D

   A-III, B-IV, C-I, D-II

Appeared in: MNS 2024

Explanation

• The correct combination is A-II, B-IV, C-I, D-III, which accurately pairs each vaccine with its standard administration route.
• Pneumococcal Conjugate Vaccine (PCV) is administered intramuscularly (IM) to ensure proper absorption and immune response.
• Rotavirus vaccine is a live attenuated vaccine given orally to induce immunity in the gut, the primary site of rotavirus infection.
• Measles vaccine is given subcutaneously (SC), a route specified for this live attenuated vaccine to ensure efficacy.
• BCG vaccine is uniquely administered intradermally (ID) to produce a localized reaction and a specific cell-mediated immune response, which is crucial for protection against tuberculosis.

Why Other Options Were Wrong

• Option B: This option incorrectly matches every single vaccine to its route. For example, it pairs Pneumococcal with Subcutaneous (should be IM) and BCG with Intramuscular (should be ID).
• Option C: This option incorrectly matches Pneumococcal vaccine to Subcutaneous, Rotavirus to Intramuscular, and Measles to Oral routes.
• Option D: This option incorrectly matches Pneumococcal vaccine to the Intradermal route and BCG to the Intramuscular route. The routes for these two vaccines have been swapped.

Related Visual

Clinical Relevance

• Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Routes of administration for common vaccines in the National Immunization Schedule as background academic context rather than a clinical decision trigger.
• Administering a vaccine via the correct route is critical for its efficacy and safety. An incorrect route can lead to a reduced immune response or an increased risk of local adverse reactions.
• Nurses play a vital role in ensuring adherence to the National Immunization Schedule, including correct administration techniques, maintaining the cold chain, and accurate documentation.
• What if the BCG vaccine is administered subcutaneously instead of intradermally? This common error can lead to a local abscess, suppurative lymphadenitis (inflammation of lymph nodes), and may result in reduced efficacy of the vaccine. The characteristic scar may not form.

How to Approach the Question

• This is a 'Match the Following' question that tests your recall of standard vaccination procedures.
• First, analyze the two lists: List I contains four common vaccines, and List II contains four routes of administration.
• Start by identifying a vaccine-route pair you are certain about. For example, BCG is famously administered intradermally (D-III).
• Scan the options to see which ones include the 'D-III' match. This immediately eliminates options B and C.
• Next, consider another well-known pair, such as Rotavirus vaccine being given orally (B-IV).
• Check the remaining options (A and D). Both contain the 'B-IV' match.

Concept Tested & Keywords

• Concept Tested: Routes of administration for common vaccines in the National Immunization Schedule.
• Stem keywords: VACCINE, ROUTE OF ADMINISTRATION, Pneumococcal vaccine, Rotavirus, Measles, BCG
• Lead-in keywords: Match
• Negative lead-in flag: false

Question ID

QEHLgw2FrTvnkwEj-RCB0J

Copy ID

Reference Book

E6 Ghai Essential Pediatrics(pp 26-904 of 913) pp. 187-189, 188-190

E6 Parks TextBook of Preventive & Social Medicine part 1 — Subpart A (pp 26-201 of 604) p. 99-101