NORCET 6 mains-2024
Applied Physiology
Medium

Excessive vomiting will cause:?

Appeared in: NORCET 6 mains-2024

Explanation

  • Excessive vomiting leads to the loss of large amounts of gastric acid (hydrochloric acid, HCl).
  • The loss of hydrogen ions (H+) from the stomach causes the pH of the extracellular fluid to rise, leading to a state of alkalosis.
  • This specific type of imbalance is known as metabolic alkalosis.
  • It is often accompanied by hypochloremia (loss of chloride) and hypokalemia (loss of potassium) as the body tries to compensate.

Why Other Options Were Wrong

  • Option A: Acidosis is a decrease in blood pH. Vomiting causes a loss of acid, which raises pH, not lowers it.
  • Option C: This option is incorrect because there is a specific and predictable outcome, which is alkalosis.
  • Option D: This option is incorrect because acidosis and alkalosis are opposite conditions; they cannot both be the direct result of the same process.

Related Visual

A flowchart illustrating the pathophysiology of metabolic alkalosis due to vomiting. It should show the stomach losing H+ and Cl-, leading to a rise in blood pH, and the subsequ...
Clinical Relevance
  • Nursing practice connection: This is primarily an exam-oriented knowledge point with limited direct bedside application, so retain Acid-Base Imbalance from Gastrointestinal Losses as background academic context rather than a clinical decision trigger.
  • Nurses must monitor patients with persistent vomiting for signs of metabolic alkalosis, such as confusion, muscle twitching, and tingling, as well as signs of dehydration.
  • Key nursing interventions include administering antiemetics to control vomiting, replacing fluids and electrolytes (especially potassium and chloride) via IV, and monitoring vital signs and lab values (blood gases, electrolytes).
  • What if? If the patient had severe, prolonged diarrhea instead of vomiting, the correct answer would be Acidosis. Diarrhea causes a significant loss of bicarbonate (a base) from the intestines, leading to metabolic acidosis.
How to Approach the Question
  • Identify the core process in the question: 'Excessive vomiting'.
  • Recall the contents of the stomach. The stomach secretes hydrochloric acid (HCl), which is highly acidic.
  • Reason about the effect of losing this substance. Losing a large amount of acid from the body will make the remaining body fluids more basic (alkaline).
  • Connect this physiological effect to the options. An increase in pH is termed 'alkalosis'.
  • Eliminate 'Acidosis' as it is the opposite condition. Eliminate 'None of these' and 'All of the above' as a specific outcome is expected.
Concept Tested & Keywords
  • Concept Tested: Acid-Base Imbalance from Gastrointestinal Losses
  • Stem keywords: Excessive vomiting
  • Lead-in keywords: will cause

Question ID

QHf-qrRxGe9VFdeDYVb1Uh

Reference Book

E6 Textbook of Biochemistry for medical StudentsDM Vasudevan Part 2 — Subpart A (pp 1-239 of 478) p. 82-84

E6 Biochemistry U Satyanarayana— Part 2 (pp 421-820 of 840) p. 99-101

E6 Physiology Guyton 4SAE Part 2B p. 77-79

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