Medicines for rare diseases, also known as orphan drugs, are specifically developed to treat conditions that affect a very small percentage of the population.
The core principle of the Essential Medicines List (EML) is to satisfy the priority health needs of the majority of the population in a cost-effective manner.
Due to the low prevalence of the diseases they treat and their typically high cost, orphan drugs do not meet the criteria of being a 'priority' for the general population's health and are therefore excluded from the EML.
Why Other Options Were Wrong
Option A: This is incorrect because a robust EML must be dynamic and include medicines to manage new public health threats and outbreaks to ensure national health security.
Option B: This is the core definition of essential medicines, as stated by the WHO. The entire purpose of the EML is to list medicines that satisfy priority health needs.
Option C: This is incorrect because medicines used in national health programmes (e.g., for TB, HIV, Malaria) are, by definition, targeting the country's priority health issues and are a crucial component of the EML.
Related Visual
Visual 1: Infographic: A visual comparison chart contrasting the key features of Essential Medicines (targeting the majority, cost-effective, high public health relevance) with Orphan Drugs (targeting rare conditions, high cost, low population-level priority).
Clinical Relevance
Nursing practice connection: Knowing Scope and criteria of the Essential Medicines List (EML) helps nurses interpret findings accurately and avoid errors in routine assessment, medication administration, and patient teaching.
Understanding the EML is crucial for nurses and healthcare administrators as it guides procurement, stocking, and prescription practices in public health facilities, ensuring that resources are used efficiently to address the most common health problems.
The EML is a key policy tool for achieving universal health coverage by making essential treatments affordable and accessible.
What if a new, highly infectious disease emerges? The EML framework allows for rapid, emergency inclusion of new, effective treatments to combat the outbreak, demonstrating its flexibility and importance in public health crises.
How to Approach the Question
First, identify the core concept of the question, which is the 'Essential drug list'.
Recognize the keyword 'Except'. This means you need to find the option that does NOT fit the criteria for inclusion in the list.
Evaluate each option against the definition of essential medicines. Ask yourself: 'Does this align with satisfying the priority health needs of the population?'
Option A (emerging infections), B (priority needs), and C (national programmes) all clearly align with serving the health needs of the population at large.
Option D (rare diseases) deals with conditions affecting a very small group, which contrasts with the 'population priority' principle. This makes it the most likely exception.
Confirm your understanding by recalling that medicines for rare diseases are a special category (orphan drugs) often handled outside the standard EML due to high costs and low prevalence.
Concept Tested & Keywords
Concept Tested: Scope and criteria of the Essential Medicines List (EML)
Stem keywords: Essential drug list, include
Lead-in keywords: Except
Negative lead-in flag: The question asks for the EXCEPTION to what is included in the Essential Drug List.
Question ID
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Practise the full Raj. CHO -2024
Attempt every question from this paper in a timed mock, then review the full solution for each one.