NORCET 2 - 2021 (shift-1)
Obstetrics & Gynaecology
Easy

A pregnant lady came to the hospital for an ANC. Which medicine would be prescribed by the on-duty doctor to prevent NTD?

Appeared in: NORCET 2 - 2021 (shift-1)

Explanation

  • Folic acid is a B-vitamin essential for DNA synthesis, which is critical for the rapid cell growth and division required for fetal development.
  • The neural tube, which develops into the brain and spinal cord, closes very early in pregnancy, typically by day 28 post-conception.
  • Adequate folic acid levels during this periconceptional period are necessary to ensure the proper closure of the neural tube, thereby preventing major birth defects like spina bifida and anencephaly.

Why Other Options Were Wrong

  • Option B: Iron is crucial for preventing maternal anemia by supporting the formation of hemoglobin and the expansion of maternal red blood cell mass.
  • Option C: Zinc is a trace element that supports immune function and cellular growth, but it is not the specific nutrient targeted for NTD prevention.
  • Option D: Phosphate is a mineral essential for building fetal bones and teeth and for energy metabolism.

Related Visual

Visual explanation — Related Visual
  • Visual 1: Diagram - A timeline showing the development of the neural tube in the first 4 weeks of gestation, highlighting the critical window for closure.
  • Visual 2: Infographic - An illustration comparing a normal spinal column with one affected by spina bifida to show the physical defect that folic acid helps prevent.
Clinical Relevance
  • Nursing practice connection: Knowing Pharmacological prevention of neural tube defects (NTDs) in pregnancy helps nurses interpret findings accurately and avoid errors in routine assessment, medication administration, and patient teaching.
  • Nurses play a crucial role in counseling all women of childbearing age about the importance of starting folic acid supplementation before conception, as the neural tube closes before many women realize they are pregnant.
  • It is vital to assess for high-risk factors (e.g., a previous NTD-affected pregnancy, use of certain antiepileptic drugs like valproic acid) that necessitate a higher prescription dose of folic acid (4 mg/day).
  • Patient education should include dietary sources of folate (leafy green vegetables, legumes, citrus fruits) but emphasize that supplementation is necessary to achieve the required protective levels.
How to Approach the Question
  • Identify the key clinical problem in the question: the prevention of Neural Tube Defects (NTDs) in a pregnant woman during an Antenatal Checkup (ANC).
  • Recall from pharmacology and obstetrics knowledge the specific micronutrient directly and most effectively linked to the prevention of NTDs.
  • Scan the options provided: Folic acid, Iron, Zinc, and Phosphate.
  • Match the recalled nutrient (Folic acid) with the options. Folic acid is the well-established, evidence-based supplement for this purpose.
  • Differentiate the primary roles of the other nutrients to confirm they are incorrect for this specific indication (Iron for anemia, Zinc for growth, Phosphate for bone health).
  • Select Folic acid as the definitive answer based on its critical role in early neural development.
Concept Tested & Keywords
  • Concept Tested: Pharmacological prevention of neural tube defects (NTDs) in pregnancy.
  • Stem keywords: pregnant, ANC, prevent NTD
  • Lead-in keywords: Which medicine
  • Clinical cues: Age/sex group narrows the expected diagnosis, intervention, or normal reference range.

Question ID

QDSDvJFeNlpCSNxCHG1MY_

Practise the full NORCET 2 - 2021 (shift-1)

Attempt every question from this paper in a timed mock, then review the full solution for each one.

More Antenatal Care, Preconceptional Counseling and Care Questions

More NORCET 2 - 2021 (shift-1) Questions